Shanxiang Zhang, MD, PhD | Pathology, Microbiology, and Immunology

Department Affiliations
Professor
Director of Hematopathology

Interests
Clinicopathological and molecular studies of hematopoietic neoplasm, particularly B-cell lymphomas

Education and Training
MD, Shanghai Medical University, China, 1990
Residency, Department of Internal Medicine, The First Hospital of Nanjing Medical University, China, 1993
MS, Medical Microbiology and Immunology, The Ohio State University, Columbus, OH, 1998
PhD, Human Cancer Genetics, The Ohio State University, Columbus, OH, 2001

National Activities
College of American Pathologists
American Society for Clinical Pathology
Society of Hematopathology
International Society on Thrombosis and Haemostasis

Notable Publications
Li Y, Xu-Monette ZY, Abramson J, Sohani AR, Bhagat G, Tzankov A, Visco C, Zhang S, Dybkaer K, Pan Z, Xu M, Tam W, Zu Y, Hsi ED, Hagemeister FB, Go H, van Krieken JH, Winter JN, Ponzoni M, Ferreri AJM, Møller MB, Piris MA, Wang Y, Zhang M, Young KH. EBV-positive DLBCL frequently harbors somatic mutations associated with clonal hematopoiesis of indeterminate potential. Blood Adv. 2023 Apr 11;7(7):1308-1311

Liu W, Cai Q, Strati P, Hagemeister F, Zhai Q, Zhang M, Li L, Fan X, Li J, Sun R, Zhang S, Yang H, Wang Z, Qian W, Iwaki N, Sato Y, Oksenhendler E, Xu-Monette Z, Young KH, Yu L. Clinical characteristics and outcomes of Castleman disease: a multicenter Consortium study of 428 patients with 15-year follow-up. Am J Cancer Res 2022;12(8). In press.

Kimpara S, Lu L, Hoang NM, Zhu F, Bates PD, Daenthanasanmak A, Zhang S, Yang DT, Kelm A, Liu Y, Li Y, Rosiejka A, Kondapelli A, Bebel S, Chen M, Waldmann TA, Capitini CM, Rui L. EGR1 Addiction in Diffuse Large B-cell Lymphoma. Mol Cancer Res. 2021 May 12. doi: 10.1158/1541-7786.MCR-21-0267. Online ahead of print

Hu Z, Pan Z, Chen W, Shi Y, Wang W, Yuan J, Wang E, Zhang S, Kurt H, Mai B, Zhang X, Liu H, Rios AA, Ma HY, Nguyen ND, Medeiros LJ, Hu S. Primary Effusion Lymphoma: A Clinicopathological Study of 70 Cases. Cancers (Basel). 2021 Feb 19;13(4):878. doi: 10.3390/cancers13040878.

Yu L, Shi M, Cai Q, Strati P, Hagemeister F, Zhai Q, Li L, Fang X, Li J, Sun R, Zhang S, Yang H, Wang Z, Qian W, Iwaki N, Sato Y, Zhang L, Li J, Oksenhendler E, Xu-Monette ZY, Young KH. A Novel Predictive Model for Idiopathic Multicentric Castleman Disease: The International Castleman Disease Consortium Study. Oncologist. 2020 Nov;25(11):963-973

Zimmermann N, Nassiri M, Zhou J, Miller AM, Zhang S. Myeloid neoplasm with a novel cryptic PDGFRB rearrangement detected by next-generation sequencing. Cancer Genet. 2020 Jun;244:55-59

Zhang S*, Wang L, Cheng L. Aberrant ERG expression associates with downregulation of miR-4638-5p and selected genomic alterations in a subset of diffuse large B-cell lymphoma. Mol Carcinog. 2019 Jun 24. doi: 10.1002/mc.23074. [Epub ahead of print].

Zhang S*, Bayerl MG. Florid splenic gamma/delta T-cell proliferation in patients with splenomegaly and cytopenias: A "high stakes" diagnostic challenge. Hum Pathol. 2017 Aug;66:216-221

Zhang S*, SunJ, FangY, NassiriM, LiuL, ZhouJ, Stohler R, Choi H, Vance GH. (2016) Signet ring cell lymphoma: Clinicopathologic, immunohistochemical and FISH studies of seven cases. Ann Diagn Pathol. 2017 Feb;26:38-42.

Xu-Monette ZY^#, Zhang S^#, Li X^#, Manyam GC, Wang XX, Xia Y, Visco C, Tzankov A, Zhang L, Montes-Moreno S, Dybkaer K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huh J, Ponzoni M, Ferreri AJ, Zhao X, Møller MB, Parsons BM, Winter JN, Piris MA, Medeiros LJ, Young KH. p63 expression confers significantly better survival outcomes in high-risk diffuse large B-cell lymphoma and demonstrates p53-like and p53-independent tumor suppressor function. Aging (Albany NY). 2016 Feb;8(2):345-65

# These authors contributed equally to this work

Detailed list of publications.