Jennifer M. Bailey-Lundberg, MA, PhD

Department Affiliations
Associate Professor
Director, Solid Tumor Cancer Immunology Section

Interests
Cancer immunology, tumor ablation, purinergic signaling, cell plasticity, gastrointestinal cancers

Education and Training
BS, Molecular Biology, University of Nebraska-Lincoln, NE, 2002
MA, Biochemistry (with Highest Distinction), University of Nebraska-Omaha, NE, 2004
PhD, Cancer Research, The NCI Designated Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, 2009
Postdoctoral Fellowship, The McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD  

National Activities
Member, American Association for Cancer Research
Member, American Gastroenterological Association
Member, American Association for the Advancement of Science
Member, American Pancreatic Association
Member, American Gastroenterological Assocation Institute Research Awards Panel
Member, Lustgarten Foundation-AACR Pancreatic Cancer Research Grants Scientific Review Committee
Ad Hoc reviewer, National Institute of Health and Department of Defense

Notable Publications
Fernández Á, Casamitjana J, Holguín-Horcajo A, Coolens K, Mularoni L, Guo L, Hartwig O, Düking T, Vidal N, Strickland LN, Pasquali L, Bailey-Lundberg JM, Rooman I, Wang YJ, Rovira M. A single-cell atlas of the murine pancreatic ductal tree identifies novel cell populations with potential implications in pancreas regeneration and exocrine pathogenesis. Gastroenterology. 2024 Jun 21:S0016-5085(24005063-7. PMID: 38908487

O’Brien, BJ, Faraoni, EY, Strickland, LN, Mota, V, Mota, S, Chen, X, Mills, TW, Eltzschig, HK, DelGiorno, KE and Bailey-Lundberg, JM. CD73-generated extracellular adenosine promotes resolution of neutrophil-mediated tissue injury and restrains metaplasia in pancreatitis FASEBJ 2023 Jan;37(1):e22684 PMID:36468677 

Faraoni, EY, Singh, K, Dai, Y, Chandra, V, Vucic, E, Mills, T, Pruski, M, Clark, T, Van Buren, G, Thosani, NC, Bynon, JS, Wray, CJ, Bar-SAgi, D, Poulson, KL, Vornik, LA, Savage, MI, Sei, S, Mohammed, A, Zhao, Z, Eltzschig, HK, Brown, PH, McAllister, F and Bailey-Lundberg, JM. CD73- dependent adenosine signaling through Adora2b drives immunosuppression in ductal pancreatic cancer. Cancer Res. 2023 Jan 31;CAN-22-2553. PMID: 36720042 

Faraoni, EY, Thosani, NC, O’Brien, B, Strickland, LN, Mota, V, Chaney, J, Cen, P, Rowe, J, Cardenas, J, Poulsenm KL, Wray, CJ, Bailey-Lundberg, JM. Radiofrequency ablation remodels the tumor microenvironment and promotes neutrophil-mediated abscopal immunomodulation in pancreatic cancer. 2023 Cancer Immunology Res. Jan 3;11(1):4-12 PMID:36367967 

Faraoni, EY, Strockland, LN, O’Brien, BJ, Barraza, J, Thosani, NC, Wray, CJ,Mills, TW and Bailey-Lundberg, JM. Radiofrequency ablation in combination with CD73 inhibitor AB680 reduces tumor growth and enhances anti-tumor immunity in a syngeneic model of pancreatic ductal adenocarcinoma 2022 Front Oncol. Sep 6;12:995027 PMID: 36147911

Singh K, Pruski M, Bland R, Younes M, Guha S, Thosani N, Maitra A Cash BD, McAllister F, Logsdon CD, Chang JT, Bailey-Lundberg, JM. Kras mutation rate precisely orchestrates ductal derived pancreatic intraepithelial neoplasia and pancreatic cancer. 2021 Laboratory Investigation Feb;101 (2):177-192. PMID: 33009500 

Zhang YU, Sanchez ER, Dutta P, Quesada P, Zoltan M, Chandra V, Horne W, Banarjee S, Burks J, Hussain P, Wang H, Gupta S, Maitra A, Bailey JM, Sahin P, Bhattacharya P and McAllister, F. Interleukin-17 modulates pancreatic cancer immunosuppression and its inhibition overcomes resistance to checkpoint blockade. 2020 J. Exp. Med. 217:12. PMID: 32860704 

Hendley, AM, Wang, YJ, Alsina, J, Ahmed, I, Lafaro, KJ, Zhang, H, Roy, N, Savidge, S, Cao, Y, Hebrok, M, Maitra, A, Reynolds, AB, Goggins, M, Younes, M, Iacobuzio-Donahue, CA, Leach, SD and Bailey, JM. 2016. p120 Catenin suppresses basal epithelial cell extrusion in invasive pancreatic neoplasia. Cancer Research. March 31. PMID: 27032419 

Bailey JM, Alsina J, Rasheed ZA, McAllister FM, Fu Y-Y, Plentz R, Zhang H, Pasricha PJ, Bardeesy N, Matsui W, Maitra A, Leach SD. DCLK1 Marks a Morphologically Distinct Subpopulation of Cells with Stem Cell Properties in Pre-invasive Pancreatic Cancer, Gastroenterology (2014), Jan;146(1):245-56. 

McAllister, FM, Bailey, JM, Alsina, J, Maitra, A, Kolls, J, Pardoll, D, Seers, C, and Leach, SD. Oncogenic Kras activates an IL-17+ hematopoietic-to-epithelial signaling axis in preinvasive pancreatic neoplasia. Cancer Cell (2014), May;25(5):621-637. PMID: 24823639 

Rhim, AD, Mirek, ET, Aiello, NM, Maitra, A, Bailey, JM, McAllister, F, Reichart, M, Beatty, GL, Rustgi, AK, Vonderheide, RH, Leach, SD, Stanger, BZ. EMT and dissemination precede pancreatic tumor formation. Cell (2012) Jan 20;148(1-2):349-61. PMID: 22265420

NCBI Bibliography Listing