UNMC_Acronym_Vert_sm_4c
University of Nebraska Medical Center

Cancer Research Faculty

Faculty Departments

  • Biochemistry and Molecular Biology
  • College of Dentistry
  • College of Nursing
  • College of Pharmacy
  • College of Public Health
  • Eppley Institute
  • Genetics Cell Biology and Anatomy
  • Internal Medicine
  • Munroe-Meyer Institute
  • Obstetrics and Gynecology
  • Ophthalmology and Visual Sciences
  • Pathology, Microbiology, and Immunology
  • Pharmacology and Experimental Neuroscience
  • Radiation Oncology
  • Radiology
  • Surgery

 

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Faculty

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Maher Abdalla, PhD
Assistant Professor, Department of Pathology, Microbiology and Immunology

Research focus: Reactive Oxygen Species (ROS), Heme Oxygenase-1 (HO-1) and immune cells in pancreatic ductal adenocarcinoma (PDAC) and prostate cancer.

Yazen Alnouti

Yazen Alnouti, PhD
Professor, Department of Pharmaceutical Sciences

Research focus: Drug metabolism and pharmacokinetics (DMPK), with a focus on the application of Bioanalytical Chemistry, in vitro and in vivo animal models to support ADMET (absorption, distribution, metabolism, excretion and toxicity) and pharmacokinetic (PK) studies; Biomarkers for hepato-biliary diseases based on bile acid metabolism by sulfation.

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Hamid Band

Hamid Band, MD, PhD
Professor, Eppley Cancer Institute

Research focus: Regulation of receptor signaling by endocytic traffic; Cbl-family and CHIP ubiquitin ligases; EHD-family endocytic recycling regulators; mouse genetic models; cancer and stem cell biology.

Vimla Band

Vimla Band, PhD
Professor and Chair, Department of Genetics, Cell Biology and Anatomy

Research focus: Delineate molecular mechanisms of early steps in transformation of mammary epithelial cells with the goal of identifying novel molecular diagnostic/prognostic markers and potential therapy targets of breast cancers.

Janina Baranowska-Kortylewicz

Janina Baranowska-Kortylewicz, PhD
Professor, Department of Radiation Oncology

Research focus: Radioimmunotherapy-related clinical studies in Hodgkin's and non-Hodgkin's lymphoma; molecular radiotherapy of peripheral T-cell lmphoma not otherwise specified using DNA-targeted agents.

Surinder Batra

Surinder K. Batra, PhD
Professor and Chair, Department of Biochemistry and Molecular Biology

Research focus: Structure/function analysis of tumor-associated genes; cancer diagnostics, cancer vaccines; monoclonal antibodies, genetic engineering of antibodies.

Raymond Bergan

Raymond Bergan, MD
Professor, Department of Internal Medicine - Oncology & Hematology

Research focus: Understanding how cancer cells regulate transformation to a high motility metastatic phenotype, and how that process can be therapeutically modulated.

Bessho

Tadayoshi Bessho, PhD
Associate Professor, Eppley Cancer Institute

Research focus: Molecular mechanism of DNA interstrand crosslink repair in mammalian cells.

Kishor Bhakat

Kishor K. Bhakat, PhD
Associate Professor, Department of Genetics, Cell Biology and Anatomy

Research focus: Understanding the molecular mechanisms and alter the damage repair pathways and gene expression in tumor cells to promote therapy resistance and tumor recurrence, and develop second line of interventions to prevent tumor recurrence and metastasis.

Chengfeng Bi

Chengfeng (Andy) Bi, PhD
Assistant Professor, Department of Internal Medicine - Oncology and Hematology

Research focus: Pathogenesis and molecular mechanism of hematological malignancies.

Piero Bianco

Piero Bianco, PhD
Associate Professor, Department of Pharmaceutical Sciences

Research focus: Stalled DNA replication fork rescue to maintain genome stability

Adrian Black

Adrian Black, PhD
Assistant Professor, Eppley Cancer Institute

Research focus: Tissue sciences; molecular biology; cell cycle; transcription; protein kinase C signaling in intestinal cells; endometrial cancer.

Jennifer Black

Jennifer Black, PhD
Professor, Eppley Cancer Institute

Research focus: Colon cancer; endometrial cancer; pancreatic cancer; cell signaling (kinases and phosphatases) cell cycle regulation; control of protein translation in cancer; protein kinase C; PP2A.

Gloria Borgstahl

Gloria Borgstahl, PhD
Professor, Eppley Cancer Institute

Research focus: Structural biology, structure-based drug design, superoxide dismutase and double-strand DNA repair by homologous recombination.

Sandipan Brahma, PhD

Sandipan Brahma, PhD
Assistant Professor, Department of Genetics, Cell Biology and Anatomy

Research focus: Mechanisms regulating chromatin structure, how cells use these mechanisms to establish and maintain gene expression programs, and the implications of these mechanisms for human health.

Siddappa Byrareddy

Siddappa Byrareddy, PhD
Professor, Department of Pharmacology & Experimental Neuroscience

Research focus: Understanding and developing therapeutics for emerging/re-emerging viruses, focusing on HIV, Zika and SARS-CoV-2.

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Scott Campbell

W. Scott Campbell, MBA, PhD
Associate Professor, Department of Pathology, Microbiology and Immunology

Research focus: Health informatics and pathology informatics.

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Kishore Challagundla, PhD
Assistant Professor, Department of Biochemistry and Molecular Biology

Research focus: Role of extra cellular vesicles (EV's) and the non-coding RNAs in affecting immunotherapy and escaping immune surveillance in pediatric cancers, in particular neuroblastoma and acute myeloid leukemia.

Pi-Wan Cheng

Pi-Wan Cheng, PhD
Professor, Department of Biochemistry and Molecular Biology

Research focus: Study of the mechanism of altered glycosylation in human disease.

Suyong Choi

Suyong Choi, PhD
Assistant Professor, Eppley Cancer Institute

Research focus: Phosphoinositide signaling pathways in cancer and immunology.

 

Dahn Clemens

Dahn Clemens, PhD
Associate Professor, Department of Internal Medicine - Cardiovascular Medicine

Research focus: Role of inflammation in the pathogenesis of cardiovascular disease; molecular mechanisms by which reactive oxygen species cause inflammation that leads to the initiation and profession of cardiovascular disease.

Sam Cohen

Samuel M. Cohen, MD, PhD
Professor, Department of Pathology, Microbiology and Immunology

Research focus: Urologic pathology, carcinogenesis and toxicology.

Martin Conda Sheridan

Martin Conda-Sheridan, PhD
Associate Professor, College of Pharmacy

Research focus: Design of complex multifunctional biomaterials and bioactive small molecules for medicinal applications.

Kenneth Cowen

Kenneth Cowan, MD, PhD
Director and Professor, Eppley Cancer Institute

Research focus: Tumor suppressor genes, breast cancer; mechanisms associated with development of multi-drug resistance and the regulation of expression of drug resistance genes in human tumor cells.

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John Davis

John S. Davis, PhD
Professor, Director of Research and Development - Olson Center for Women's Health, Department of Obstetrics and Gynecology

Research focus: Women's health; Reproductive endocrinology and cancer; Mechanisms of hormone action.

Rebecca Oberley-Deegan

Rebecca Oberley-Deegan, PhD
Professor, Department of Biochemistry and Molecular Biology

Research focus: Role of free radicals signaling to transform fibroblasts and inflammatory cells in normal tissue, which results in damage to these tissues; understanding the mechanisms by which ROS promote radiation induced fibrosis and prostate cancer progression.

Punita Dhawan

Punita Dhawan, PhD
Professor, Department of Biochemistry and Molecular Biology

Research focus: Development of novel therapeutic targets for Gastrointestinal Cancer progression and chemoresistance; Role of signaling pathways and cancer stem cells involved in this process using cell culture, mouse and organoid models.

Jixin Dong

Jixin Dong, PhD
Associate Professor, Eppley Cancer Institute

Research focus: Hippo signaling and cancer; Chemotherapeutic drug resistance.

Bin Duan, PhD

Bin Duan, PhD
Associate Professor, Department of Internal Medicine - Cardiology

Research focus: Integrate novel biomaterials, advanced biofabrication of tissue engineering to create multi-scale complexity within engineered tissue to understand the fundamentals of cell-material interactions and mimic the native tissue for tissue regeneration.

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Dalia ElGamal, PhD

Dalia Elgamal, PhD
Assistant Professor, Eppley Cancer Institute

Research focus: Pathogenesis of B-cell malignancies, including immunosuppressive microenvironmental interactions and the gut microbiome, and evaluating novel anti-tumor therapeutics strategies.

Jim Eudy

James Eudy, PhD
Associate Professor, Director of UNMC DNA Microarray and Sequencing Core Facility, Department of Genetics, Cell Biology and Anatomy

Research focus: Next Generation DNA Sequencing strategies for rare Mendelian disease gene identification and functional genomic technologies; biomedical interest in cancer, cardiovascular disease and virology.

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Kurt Fisher, MD, PhD

Kurt Fisher, MD, PhD
Assistant Professor, Department of Pathology, Microbiology and Immunology

Research focus: Basic and transitional research with the goal of identifying and evaluating novel targets for therapy in gastrointestinal tumors with K-Ras mutations; GI tract, liver, and solid organ transplant pathology.

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Jered Garrison

Jered Garrison, PhD
Professor, College of Pharmacy

Research focus: Targeted molecular imaging and radiotherapeutic agent design; development of cancer-specific prodrugs; polymer based drug delivery systems.

Gargi Ghosal

Gargi Ghosal, PhD
Assistant Professor, Department of Genetics, Cell Biology and Anatomy

Research focus: Understand the basic science underlying replication stress response in cancer and aging; identify new targets and bio-markers for cancer therapy and facilitate the development of strategies to overcome drug resistance and improve cancer therapies.

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Kyle Hewitt, PhD

Kyle Hewitt, PhD
Assistant Professor, Department of Genetics, Cell Biology & Anatomy

Research focus: Multidisciplinary approaches to identify gene regulation networks and cell signaling mechanisms that control blood production during development and/or regeneration following disease or injury.  Transcriptional and epigenetic mechanisms that cause hematologic disorders and mechanisms that regulate the function of hematopoietic stem and projenitor cells.

Sarah Holstein

Sarah Holstein, MD, PhD
Professor, Department of Internal Medicine - Oncology and Hematology

Research focus: Development of novel agents for the treatment of multiple myeloma and pancreatic cancer, with a particular focus on Rab inhibitors of the isoprenoid biosynthetic.

Corey Hopkins

Corey Hopkins, PhD
Associate Professor, Pharmaceutical Sciences

Research focus: Design, synthesis and optimization of biologically active small molecules as in vivo probes, drug discovery lead compounds and preclinical candidates.

Kate Hyde

R. Katherine (Kate) Hyde, PhD
Associate Professor, Department of Biochemistry and Molecular Biology

Research focus: Understand the mechanisms that regulate leukemia development; develop treatments for hematological malignancies.

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Javeed Iqbal

Javeed Iqbal, PhD
Professor, Department of Pathology, Microbiology and Immunology

Research focus: Molecular signatures to improve diagnosis and outcome prediction in Non-Hodgkin’s Lymphoma; gene expression profiling and pathway targeted therapy in peripheral T-cell lymphoma; characterization of key molecular signatures in natural killer cell malignancies.

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Maneesh Jain

Maneesh Jain, PhD
Professor, Department of Biochemistry and Molecular Biology

Research focus: Development of genetically engineered antibody fragments for improved radioimmunotherapy for solid tumors; development of serum assays for the early diagnosis of lethal pancreatic cancer.

Keith Johnson

Keith R. Johnson, PhD
Professor, Eppley Cancer Institute

Research focus: The role the cell adhesion molecules (cadherins) play in metastasis.

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Adam Karpf

Adam R. Karpf, PhD
Professor, Eppley Cancer Institute

Research focus: Ovarian cancer biology and therapeutics; Cancer epigenetics.

So-Youn Kim, PhD

So-Youn Kim, PhD
Assistant Professor, Department of Obstetrics and Gynecology

Research focus: Oncofertility, cachexia, ovarian cancer.

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Robert Lewis

Robert Lewis, PhD
Professor, Eppley Cancer Institute

Research focus: Defining intracellular mechanisms required for the epithelia-mesenchymal transition (EMT) and the formation and maintenance of cancer stem cells.

Ming-Fong Lin

Ming-Fong Lin, PhD
Professor, Department of Biochemistry and Molecular Biology

Research focus: Mechanism of cell growth regulation by steroids via cross-talk of ROS and tyrosine phosphorylation signaling.

Yutong Liu

Yutong Liu, PhD
Associate Professor, Department of Radiology

Research focus: Neuroimaging and image processing.

Matthew Lunning

Matthew Lunning, DO
Assistant Professor, Department of Internal Medicine – Oncology and Hematology

Research focus: Rare hematologic malignancies with a focus on early drug development and experimental correlates that leads to enhanced knowledge of how to treat hematologic malignancies.

Xu Luo

Xu Luo, PhD
Professor, Eppley Cancer Institute

Research focus: Molecular mechanisms and signaling pathways in cell death and survival in cancer cells.

Quan Li

Quan Ly, MD, FACS
Professor, Department of Surgery

Research focus: Study of the role of cadherins in metastatic cancer cell signaling and effect of cadherin mutations on cell adhesion and cell motility.  Evaluate NBL1 function by re-expressing NBL1 in cancer cells.  Develop novel therapies for pancreatic cancers.  Study the role of survivin in pancreatic cancers.

Yuri Lyubchenko

Yuri Lyubchenko, PhD, DrSc
Professor, College of Pharmacy

Research focus: Nanoscale structure, dynamics and interactions – seeing and manipulating biomolecules.

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Sidharth Mahapatra

Sidharth Mahapara, MD, PhD
Associate Professor, Department of Pediatrics

Research focus: Elucidating pathophysiologic mechanisms triggering aggressive pediatric brain tumors using transcriptomic analyses to hone in on essential signaling pathways and to test synthetic inhibitors of these pathways; Repurposing FDS-approved drugs for treatment of aggressive pediatric brain tumors.

Luis Marky

Luis Marky, PhD
Professor, College of Pharmacy

Research focus: Biophysical chemistry and molecular forces that control the conformational stability and flexibility of nucleic acids, including Okazaki fragments, hairpin loops, intramolecular triplexes, G-quadruplexes, C-quadruplexes, and three- & four-arm DNA junctions and their interaction with drugs.

Grinu Mathew

Grinu Mathew, PhD
Assistant Professor, Eppley Cancer Institute

Research focus: Genetic and epigentic regulation of prostate cancer metastasis.

Benita McVicker

Benita McVicker, PhD
Associate Professor, Department of Internal Medicine - Gastroenterology-Hepatology

Research focus: Alcohol liver injury and mechanisms.

Aaron Mohs

Aaron Mohs, PhD
Associate Professor, College of Pharmacy

Research focus: Development of new florescent imaging contrast agents to guide surgical removal of tumors; developing new drug delivery systems that multiple myeloma; developing pathogen biosensors.

Justin Mott

Justin L. Mott, PhD, MD
Professor, Department of Biochemistry and Molecular Biology

Research focus: Receptor tyrosine kinase and microRNA regulation of apoptosis in liver cancer and bile duct injury.

DJ Murry

DJ Murry, PharmD
Professor, Department of Pharmacy Practice

Research focus: Ways to individualize drug therapy using pharmacokinetic and pharmacogenomics information; from in vitro metabolism and transport studies, animal pharmacokinetic studies, to clinical studies evaluating drug therapy in patients.

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Wasim Nasser, PhD

Wasim (Mohd) Nasser, PhD
Associate Professor, Department of Biochemistry & Molecular Biology

Research focus: Novel therapeutic strategies for immunosuppressive and tumor-supportive microenvironments of metastatic breast and lung cancers.

Amar Natarajan

Amarnath (Amar) Natarajan, PhD
Professor, Eppley Cancer Institute

Research focus: Developing novel target and mechanism specific therapeutics.

Ali Nawshad

Ali Nawshad, PhD
Professor, College of Dentistry

Research focus: Transforming Growth Factor (TGF) ß signaling during palate development; mechanisms of Epithelial-Mesenchymal Transition (EMT) by TGFß in HNSCC; role of TGFß signaling during dentinogenesis.

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Gregory Oakley

Gregory Oakley, PhD
Professor, College of Dentistry – Oral Biology

Research focus: DNA damage and repair involving signal transduction pathways that regulate the cellular response to DNA damage and how alterations in these pathways contribute to mutagenesis and, ultimately, carcinogenesis.

Michael Ouellette

Michael M. Ouellette, PhD
Professor, Department of Internal Medicine - Gastroenterology and Hepatology

Research focus: Molecular mechanisms that determine the lifespan of human cells, including telomeres and telomerase.  Role of the small GTPases K-Ras and Rac1 in the development of pancreatic cancer and its response to conventional therapies.

David Oupicky

David Oupicky, PhD
Professor, College of Pharmacy

Research focus: Design on multifunctional nanoparticles and polymers withe applications in the treatment of metastiatic cancer, inflammatory bowel disease, and acute kidney injury.

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Youri Pavlov

Youri Pavlov, PhD
Professor, Eppley Cancer Institute

Research focus: Cellular systems of mutagenesis and antimutagenesis.

Thomas Petro

Thomas Petro, PhD
Professor, College of Dentistry

Research focus: Using molecular immunobiology approaches to explore intrinsic pathways to or novel therapeutics for expression and control of cytokines to prevent chronic viral infections, autoimmune disease and/or inflammatory diseases.

Armen Petrosyan

Armen Petrosyan, MD, PhD
Associate Professor, Department of Biochemistry and Molecular Biology

Research focus: Mechanism of Golgi alteration in advanced prostate cancer: focus on aberrant glycosylation; role for non-muscle Myosin IIA in alcohol-induced Golgi fragmentation.

Larisa Poluektova

Larisa Poluektova, MD, PhD
Professor, Department of Pharmacology and Experimental Neuroscience

Research focus: Pathogenesis and treatment of HIV-1 associated dementia; translational mouse models for human-specific diseases.

Moorthy Ponnusamy

Moorthy Ponnusamy, PhD
Associate Professor, Department of Biochemistry and Molecular Biology

Research focus: Cancer stem cells; metastasis; progression of pancreatic cancer.

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Prakash Radhakrishnan

Prakash Radhakrishnan, PhD
Assistant Professor, Eppley Cancer Institute

Research focus: Glycobiology of pancreatic cancer; autocrine and paracrine cell signaling mechanisms; developing therapeutics for pancreatic cancer.

Subu Ramanathan

Subu Ramanathan, PhD
Assistant Professor, Department of Genetics, Cell Biology and Anatomy

Research focus: Principles that underpin how cells with divergent sizes pack into epithelial tissue and how alterations in cellular packing influence tissue homeostasis.

Angie Rizzino

Angie A. Rizzino, PhD
Professor, Eppley Cancer Institute

Research focus: Molecular mechanisms that regulate the proliferation of cancer stem cells and pluripotent stem cells.

Kerry Rodabaugh

Kerry Rodabaugh, MD
Professor, Department of Obstetrics and Gynecology

Research focus: Gynecologic oncology.

Jordan Rowley

Jordan Rowley, PhD
Assistant Professor, Department of Genetics, Cell Biology & Anatomy

Research focus: 3D organization of DNA within the nucleus.

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Micah Schott

Micah Schott, PhD
Assistant Professor, Department of Biochemistry & Molecular Biology

Research focus: Cell biology of lipids in metabolic disease.

Polina Shcherbakova

Polina Shcherbakova, PhD
Professor, Eppley Cancer Institute

Research focus: Mechanisms controlling genome stability in eukaryotic cells, particularly the functions of DNA polymerases, DNA replication fidelity and the relationship between DNA polymerase defects and cancer.

Jawed Siddiqui

Jawed Siddiqui, PhD
Assistant Professor, Department of Biochemistry and Molecular Biology

Research focus: Bone metastasis, bone microenvironment, chemokines and cytokines, osteoimmunology, bone-muscle cross-talk, and cancer therapeutics.

Amar Singh

Amar Singh, PhD
Associate Professor, Department of Biochemistry and Molecular Biology

Research focus: Molecular mechanisms of inflammatory bowel disease and colon cancer; renal pathobiology.

Rakesh Singh

Rakesh K. Singh, PhD
Professor, Department of Pathology, Microbiology and Immunology

Research focus: Tumor growth and metastasis, angiogenesis, tumor immunology, cytrokine biology.

Joyce Solheim

Joyce Solheim, PhD
Professor, Eppley Cancer Institute

Research focus: Mechanisms regulating the immune response to tumors and infectious pathogens, and development of new immunotherapies.

Paul Sorgen

Paul Sorgen, PhD
Professor, Department of Biochemistry and Molecular Biology

Research focus: Advancing our understanding of the fundamental mechanisms of gap junction regulation in the heart, with particular interest and expertise in protein-protein interactions mediated by the carboxyl terminal domain of connexins.

Jingjing Sun

Jingjing Sun, PhD
Assistant Professor, Department of Pharmaceutical Sciences

Research focus: Development of effective nanoformulation gene/drug delivery systems for enchanced cancer therapies and other diseases.

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Tahir Tahirov

Tahir Tahirov, PhD
Professor, Eppley Cancer Institute

Research focus: Reveal the structure basis of the mechanisms covering the key stages in the expression and duplication/repair of genes and to learn how the disease-related mutations in proteins disrupt these key processes.

Melissa TeohFitzgerald

Melissa Teoh-Fitzgerald, PhD
Assistant Professor, Department of Biochemistry and Molecular Biology

Research focus: Role of oxidative tumor microenvironment in regulating the reciprocal tumor-stroma interactions.

Paul Trippier

Paul Trippier, PhD
Associate Professor, Department of Pharmaceutical Sciences

Research focus: Small molecule drug discovery for cancer and neurodegenerative diseases.

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Joseph Vetro

Joseph Vetro, PhD
Assistant Professor, College of Pharmacy

Research focus: Developing novel synthetic targeted drug and gene delivery nanocarriers for the anti-angiogenesis treatment of cancer; improving development paradigms for targeted bioimaging and drug delivery nanocarriers; developing subunit vaccines based on the novel adjuvant, EP67.

Saraswathi Viswanathan

Saraswathi Viswanathan, PhD
Assistant Professor, Department of Internal Medicine - Diabetes, Endocrine and Metabolism

Research focus: Determine the role of obesity in modulating the pathogenesis of insulin resistance, alcohol-associated liver injury, and pancreatic cancer.

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James Wahl

James Wahl, PhD
Professor, College of Dentistry

Research focus: Understand the role of desmosomes play in maintaining the normal phenotype of squamous epithelial tissues and to determine if their alteration during tumorigenesis influences cell motility, metastasis and signaling.

Shibiao Wan

Shibiao Wan, PhD
Assistant Professor, Department of Genetics, Cell Biology and Anatomy

Research focus: Bioinformatics, machine learning and computational biology, especially in single cell analysis, multi-omics analysis, spatial transcriptomics, cancer research, intelligent healthcare and precision medicine.

Gus Wang

Guangshun (Gus) Wang, PhD
Professor, Department of Pathology, Microbiology and Immunology

Research focus: Develop novel antimicrobials by combining structural biology and database with in vitro and in vivo toxicity and efficacy studies.
Nicholas Woods

Nicholas Woods, PhD
Assistant Professor, Eppley Cancer Institute

Research focus: Systems biology based analysis of cancer signaling pathways.

Ashley Wysong

Ashley Wysong, MD, MS
Professor, Department of Dermatology

Research focus: Skin cancer treatment and epidemiology.

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Jingwei Xie

Jingwei Xie, PhD
Professor, Department of Surgery-Transplant

Research focus: Synthesis, surface modification, self-assembly of materials at nanometer scale to address problems in the field of tissue engineering, regenerative medicine and drug/gene delivery.

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Ying Yan

Ying Yan, PhD
Associate Professor, Department of Radiation Oncology

Research focus: Rac1 GTPase in chemo/radiation response of breast cancer; Protein Phosphatase 2A in oncogenesis and cancer progression.

Jae Hyuk Yoo 

Jae Hyuk Yoo, PhD
Assistant Professor, Department of Ophthalmology & Visual Sciences

Research focus: Uveal melanoma.

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Chi (Kevin) Zhang

Chi (Kevin) Zhang, MD, PhD
Associate Professor, Department of Radiation Oncology

Research focus: Development of novel strategies for delivery of therapies to brain tumors.

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