Bioinformatics & Systems Biology Faculty
Faculty Departments
- Anesthesiology
- Biochemistry and Molecular Biology
- Biology (UNO)
- Cellular and Integrative Physiology
- College of Pharmacy
- Computer Science (UNO)
- Eppley Cancer Institute
- Genetics Cell Biology and Anatomy
- Information Science and Technology (UNO)
- Interdisciplinary Informatics (UNO)
- Internal Medicine - DEM
- Mathematics (UNO)
- Munroe-Meyer Institute
- Neurological Sciences
- Obstetrics and Gynecology
- Pathology, Microbiology, and Immunology
- Pharmacology and Experimental Neuroscience
- Pharmacy Practice and Science
- Surgery
Faculty
Maher Y. Abdalla, PhD Research focus: Reactive Oxygen Species (ROS), Heme Oxygenase-1 (HO-1) and immune cells in pancreatic ductal adenocarcinoma (PDAC) and prostate cancer. |
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Hesham Ali, PhD Research focus: Developing secure and energy-aware wireless infrastructure to address tracking and monitoring problems in medical environments, particularly to study mobility profiling for various groups and to conduct a population analysis approach to advancing healthcare research. |
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Hamid Band, MD, PhD Research focus: Regulation of receptor signaling by endocytic traffic; Cbl-family and CHIP ubiquitin ligases; EHD-family endocytic recycling regulators; mouse genetic models; cancer and stem cell biology. |
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Vimla Band, PhD Research focus: Delineate molecular mechanisms of early steps in transformation of mammary epithelial cells with the goal of identifying novel molecular diagnostic/prognostic markers and potential therapy targets of breast cancers. |
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Kiran Bastola, PhD Research focus: Computational biology including gene regulation with noncoding RDA, mining for interesting patterns form genomic sequences for use in molecular diagnostics, public health, secondary metabolism and biology of the mitochondria in disease, as well as extreme environments. |
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Kenneth W. Bayles, PhD Research focus: Staphylococcus aureus infections; biofilm development; the control of bacterial programmed cell death. |
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Kishor K. Bhakat, PhD Research focus: Understanding the molecular mechanisms and alter the damage repair pathways and gene expression in tumor cells to promote therapy resistance and tumor recurrence, and develop second line of interventions to prevent tumor recurrence and metastasis.er. |
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Jennifer Black, PhD Research focus: Colon cancer; endometrial cancer; pancreatic cancer; cell signaling (kinases and phosphatases) cell cycle regulation; control of protein translation in cancer; protein kinase C; PP2A. |
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Sandipan Brahma, PhD Research focus: Mechanisms regulating chromatin structure, how cells use these mechanisms to establish and maintain gene expression programs, and the implications of these mechanisms for human health. |
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Keely Buesing, MD, FACS Research focus: Large animal and pulmonary cellular investigation of novel therapeutics targeting Acute Respiratory Distress Syndrome (ARDS). |
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Siddappa Byrareddy, PhD Research focus: Understanding and developing therapeutics for emerging/re-emerging viruses, focusing on HIV, Zika and SARS-CoV-2. |
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W. Scott Campbell, MBA, PhD Research focus: Health informatics and pathology informatics. |
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Kishore Challagundla, PhD Research focus: Role of extra cellular vesicles (EV's) and the non-coding RNAs in affecting immunotherapy response and escaping immune surveillance in pediatric cancers, in particular neuroblastoma and acute myeloid leukemia. |
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Pi-Wan Cheng, PhD Research focus: Study of the mechanism of altered glycosylation in human disease. |
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Parvathi Chundi, PhD Research focus: Machine learning algorithms for unstructured data collections; serious games; Big Data Frameworks. |
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Jonathan Clayton, PhD Research focus: Host-microbiome interactions in humans and nonhuman primates. |
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Kate Cooper (Dempsey), PhD Research focus: Microbiome analysis related to diet and consumer/patient health; bioinformatics education. |
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John S. Davis, PhD Research focus: Women's health; Reproductive endocrinology and cancer; Mechanisms of hormone action. |
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Paul Davis, PhD Research focus: Investigating and developing novel approaches to prevent and treat human parasitic infections, using approaches that include molecular biology, bioinformatics, -omics, high-content imaging, and genetics. |
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Andrew Dudley, PhD Research focus: Mechanisms that regulate the development and homeostasis of musculoskeletal tissue using methods from embryology, molecular biology, cell biology, genetics and tissue engineering, with the goal of generating novel therapies for regenerative medicine. |
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Howard S. Fox, MD, PhD Research focus: Neurodegeneration, viral infections, single cell analyses of the brain, translational research in neuroscience. |
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Lie Gao, MD, PhD Research focus: Role of skeletal muscle Nrf2 in exercise-induced cardioprotection, with a focus of extracellular vesicle-mediated cell-to-cell antioxidant communication, by employing skeletal muscle-specific transgenic mouse lines. |
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Howard E. Gendelman, MD Research focus: Development and testing of HIV-1 cure strategies; Basic and clinical studies on novel medicines to treat Parkinson's disease. |
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Dario Ghersi, MD, PhD Research focus: Large-scale cancer genomics datasets, integrating different types of data (including protein structure) to gain insight into the molecular bases of cancer and immune system function. |
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Gargi Ghosal, PhD Research focus: Understand the basic science underlying replication stress response in cancer and aging; identify new targets and bio-markers for cancer therapies and facilitate the development of strategies to overcome drug resistance and improve cancer therapies. |
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Stacey Gilk, PhD Research focus: Microbial pathogenesis; Coxiella, Rickettsia |
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Karen Gould, PhD Research focus: Estrogen receptor alpha regulation of B cell receptor signaling, B cell fate, and lupus pathogenesis. B cell transcriptomics and genomics. |
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Chittibabu (Babu) Guda, PhD Research focus: Development and application of computational methods for genomic data analyses including cancer genomics, functional annotation of proteins, pathways, networks and systems in biomedical research. |
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Rebekah Gundry, PhD Research focus: Development and application innovative mass spectrometry (MS) technologies, bioinformatics tools, and methodologies to transform our understanding of cell surface proteins and glycans, and answer outstanding questions in stem cell biology and cardiac pathology. |
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Kyle Hewitt, PhD Research focus: Hematopoitic stem and progenitor cell control of blood production during development and/or regeneration following disease or injury; transcriptional and epigentic mechanisms that cause hematologic disorders; tissue and cellular heterogeneity; CRISPR/Cas9-mediated disruption of gene regulatory networks and cell signaling mechanisms. |
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Michael A. (Tony) Hollingsworth, PhD Research focus: Basic and translational research in pancreatic cancer, including investigation of the biology of tumor progression, discovery and validation of biomarkers of early detection and disease progression, development and testing of novel therapeutics, including targeted therapies and immunotherapies. |
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Tammy L. Kielian, PhD Research focus: Host-pathogen interactions, immunology, neuroimmunology, translational therapeutics. |
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Marilynn Larson, PhD Research focus: Host and intracellular pathogen interactions, and determining the mechanisms that allow the Tier 1 select agent Francisella tularensis to persist and rapidly replicate within infected macrophages. |
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Ming-Fong Lin, PhD Research focus: Mechanism of cell growth regulation by steroids via cross-talk of ROS and tyrosine phosphorylation signaling. |
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Guoqing Lu, PhD Research focus: Theoretical and applied bioinformatics, with a focus on comparative genomics and evolutionary informatics. |
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Mahbubul Majumder, PhD Research focus: Exploratory data analysis; data visualization and visual inference; statistical modeling; data science. |
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Luis Marky, PhD Research focus: Biophysical chemistry and molecular forces that control the conformational stability and flexibility of nucleic acids, including Okazaki fragments, hairpin loops, intramolecular triplexes, G-quadruplexes, C-quadruplexes, and three- & four-arm DNA junctions and their interaction with drugs. |
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Grinu Mathew, PhD Research focus: Genetic and epigentic regulation of prostate cancer metastasis. |
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Karoly Mirnics, MD, PhD Research focus: Animal models of neurodevelopmental and psychiatric disorders; effects of Gene-Environmental-Drug interactions on the developing brain; role of disrupted cholesterol biosynthesis of brain function - all using genetic, molecular, cellular and biochemical tools in our studies, coupled with drug screening and mouse behavioral assessments. |
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Paras Kumar Mishra, PhD Research focus: MicroRNomics of cardiovascular diseases and diabetic cardiomyopathy. |
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DJ Murry, PharmD Research focus: Ways to individualize drug therapy using pharmacokinetic and pharmacogenomics information; from in vitro metabolism and transport studies, animal pharmacokinetic studies, to clinical studies evaluating drug therapy in patients. |
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Caroline Ng, PhD Research focus: Biology and pathogenesis of Plasmodium falciparum, genetic and molecular mechanisms underlying drug resistance. |
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Robert B. Norgren, PhD Research focus: Use of nonhuman primate genomics to better understand human genetic disease. |
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Scot Ouellette, PhD Research focus: Chlamydial microbiology: bacterial cell division, gene regulation, host-pathogen interactions. |
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Gurudutt N. Pendyala, PhD Research focus: Animal models of addiction, sex differences in drug abuse; Synaptic biology; Epigenetic regulation, role of microRNAs at the synapse in drug addiction, mechanisms and role in gene regulation; Prenatal drug exposure and synaptic development; Integrative Systems Biology approach to understand synaptic aberrations in chronic drug abuse; High input technologies-genomics, mass spectrometry-based proteomics and metabolomics. |
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Matthew Rizzo, MD, FAAN Research focus: Memory disorders; behavioral consequences of aging and neurological disorders. |
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Jim Rogers, PhD Research focus: Mathematical biology. |
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Don Ronning, PhD Research focus: Discovery and development of anti-infective and anti-cancer compounds. |
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Jordan Rowley, PhD Research focus: 3D organization of DNA within the nucleus. |
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Polina Shcherbakova, PhD Research focus: Mechanisms controlling genome stability in eukaryotic cells, particularly the functions of DNA polymerases, DNA replication fidelity and the relationship between DNA polymerase defects and cancer. |
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Jawed Siddiqui, PhD Research focus: Bone metastasis, bone microenvironment, chemokines and cytokines, osteoimmunology, bone-muscle cross-talk, and cancer therapeutics. |
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William Tapprich, PhD Research focus: Understanding the structure and function of viral RNA molecules, particularly enteroviral genomic RNA. |
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Saraswathi Viswanathan, PhD Research focus: Determine the link between obesity and cardiovascular disease. |
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Shibiao Wan, PhD Research focus: Bioinformatics, machine learning and computational biology, especially in single cell analysis, multi-omics analysis, spatial transcriptomics, cancer research, intelligent healthcare and precision medicine. |
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Hanjun Wang, MD Research focus: Exercise physiology; cardiovascular research; respiratory research; neuroal science. |
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Jieqiong Wang, PhD Research focus: Machine learning; medical imaging processing/analysis; brain development and aging; disease diagnosis/prognosis. |
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David Warren, PhD Research focus: Cognitive neuroscience investigations of cognition (especially memory) and related brain networks that combine neuroimaging, neuropsychological, and neurostimulation methods. |
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Nicholas Woods, PhD Research focus: Systems biology based analysis of cancer signaling pathways. |
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Ying Yan, PhD Research focus: Tumorigenesis, cancer progression and metastasis, and development of new anticancer agents. |
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