Research
The Regenerative Medicine Program seeks to establish approaches that generate new therapies for disease. The types of research activities undertaken will utilize:
- Cellular therapies, involving both adult and embryonic stem cells
- Translational research leading to clinical trials
- Restoration with synthetic and cellular components
- Collaboration with bioengineering facility at UNL
- Stem cell differentiation
- Biotech collaborations
- Induced pluripotent stem cells
Focus Areas
Biomaterials Regeneration
Biomaterials in regenerative medicine serve dual purposes: as scaffolds supporting cell growth and structure formation, and as delivery systems for signaling molecules that enhance tissue regeneration. At UNMC, researchers develop multifunctional biomaterials to study tissue development, create in vitro models for drug screening, and engineer tissues for surgical treatment of diseases.
Bone Development and Regeneration
Embryonic bone formation follows regulated developmental patterns that, once understood, can be applied to regenerate bone tissue damaged by injury or disease.
Pancreas Regeneration
Once damaged, the body’s insulin-producing cells don’t regenerate. UNMC scientists are working to make history by replacing those damaged cells with healthy tissue, thereby directly addressing one of the problems of diabetes.
Vascular Regeneration
Arteriovenous fistulas, surgically created connections between arteries and veins for vascular access, often fail to mature properly. UNMC researchers study vein maturation mechanisms to improve success rates for dialysis patients.