Office of the Vice Chancellor for Research

- Research Resources Overview
- - Shared Cores
    Our cores and shared resources offer a wide range of services to meet your research goals.
  - Shared Equipment
    Shared equipment is available to University of Nebraska and external researchers.
- - Study Intake
    Take the first step in conducting clinical research on campus by completing the study intake process.
  - Standard Operating Procedures
    Review the standard operating procedures of our clinical research program.
  - Education
    Learn more about training and education opportunities available for the campus clinical research community.
  - Recruitment
    Discover resources, guidelines and support to make the research recruitment process streamlined.
- - Software
    Find the software and applications that can take your research to the next level.
  - Data Management
    Explore data management plan creation and storage options to keep research data safe and secure.
  - IT Resources
    Access key tools, workshops and seminars with IT resources available.
  - Network Connectivity
    Learn about lab network connectivity available across campus.
- - Buildings
    Research buildings offer a wide-range of lab spaces and facilities to meet researchers' needs.
  - Space Policy
    Research space is assigned based on a merit-based system.
- Programs & Centers Overview
- Approved Centers
  Board of Regents Centers enhance faculty research and academic efforts.
- Major Programs
  Major research programs drive innovation in critical areas of biomedical science.
- Compliance Overview
- Institutional Review Board
  The IRB reviews human subjects research projects and ensures the protection of participants.
- Institutional Biosafety Committee
  The IBC ensures the health and safety of all personnel working with biohazardous agents.
- Institutional Animal Care & Use Committee
  The IACUC reviews research and provides guidance to maintain the highest standards of animal welfare.
- Investigational Device Review Committee
  The IDRC reviews investigational devices and approved devices provided by sponsors for use in clinical research studies.
- Funding Overview
- Sponsored Programs Administration
  Our office manages the full lifecycle of sponsored research projects.
- Funding Opportunities
  Find internal and external research funding opportunities.
- Grant Editing
  Grant review and editing resources are available to UNMC researchers.
- UneHealth
  UNeHealth supports clinical research projects throughout the life of industry-funded contracts.
- Innovation Overview
- Tech Transfer
  Our technology commercialization ecosystem helps researchers transform scientific discoveries into real-world solutions.
- Economic Development
  Through collaborations with strategic partners, we create pathways for innovation to drive economic growth.

— Office of the Vice Chancellor for Research — Research Resources — Cores & Shared Resources — UNMC Cores and Shared Resources — Multiphoton Intravital & Tissue Imaging Core Facility — Instruments and Services

Instruments and Services

Olympus FVMPE-RS Multiphoton Microscope

This microscope is a a multichannel, multiphoton excitation system specifically tailored for intravital and deep tissue imaging. It delivers high speed (up to millisecond imaging) for rapid in vivo imaging of physiological responses, near infrared excitation for deep tissue imaging. The Olympus FVMP-RS system is additionally equipped with 458 and 588 nm stimulation laser lines for photobleaching, light stimulation and/or photoactivation of various fluorescent or caged constructs.

Neurotar Mobile Home Cage

The Neurotar Mobile Home Cage integrate real-time imaging with behavioral/locomotion tracking. Researchers can perform real-time imaging of neuronal activity concurrently with activity tracking using this system.

Additional Instrumentation

Instrument details can be found listed below. Note this is not an all-inclusie list and you may contact us for individual imaging needs.

Olympus FVMPE-RS advanced multiphoton microscope
Spectra-Physics InSight X3 dual-line (1045nm, 680 -1300 nm), tunable multiphoton/NIR laser
Multiphoton excitation for traditional fluorophores (blue to long range red) and second and third harmonic imaging.
Additional 458 and 588 nm stimulation laser lines for photobleaching, light stimulation and/or photoactivation of various fluorescent or caged constructs.
Multi-alkaline PMTs and two gallium arsenide phosphide (GaAsP) detectors are available for multichannel detection, the latter delivering optimum sensitivity.
A high-speed Resonant scanner supports imaging 30 frames/sec (512 x 512 pixels) and 438 frames/sec (512 x 32 pixels) to measure rapid changes in fluorescent signals.
Neurotar Mobile Home Cage
Stage heater for extended intravital imaging
Attached room available for sample preparation.
Olympus software supports optical Z-sectioning, 3D imaging, multi-location imaging at individual and multiple time points, and fluorescence quantification.