UNMC_Acronym_Vert_sm_4c
University of Nebraska Medical Center

Harold D. Schultz, PhD

Professor, UNMC Department of Cellular and Integrative Physiology

Harold D. Schultz, PhD

Harold D. Schultz, PhD, is professor with distinction in the UNMC Department of Cellular and Integrative Physiology, a fellow for the American Physiology Society, and fellow and golden member of the American Heart Association.

His professional experience spans more than 33 years as a faculty member at UNMC. He has taught respiratory physiology for medical, graduate and allied health curricula over this period.

Dr. Schultz's research background and expertise is in the field of autonomic control of cardiovascular and respiratory function in health and disease in preclinical and clinical settings, with more than 130 publications funded continuously by grants from the National Institutes of Health or the  American Heart Association. Dr. Schultz retired from research in 2022. He currently teaches and mentors for the department.

Dr. Schultz has been a senior editor for the Journal of Physiology for the past 12 years. He has led several special issues and symposium reviews and has overseen manuscript submissions over a broad range of physiology topics.

Education
  • Bachelor's: University of Illinois, Champaign-Urbana, cum laude, with distinction in physiology, 1974
  • Master's: University of Illinois, Champaign-Urbana, physiology, 1976
  • Ph.D.: University of Illinois, Champaign-Urbana, physiology, 1979
Research

Research focus: Autonomic neuroscience.

Dr. Schultz's research has provided insights into the role of hypoxic stress and flow mediate transcription factors for activation of autonomic sensory nerve endings during normal and patho-physiological states (myocardial infarction and reperfusion, and chronic heart failure) and the influence of these inputs on sympathetic neural activity, and cardio-renal and respiratory functions.

Grants from the National Institutes of Health and the American Heart Association continuously funded these and other neuro-circulatory related studies under his direction over more than 30 years, including a Program Project Grant for 25 years.

Dr. Schultz retired from research in 2022.

Selected Publications
  • Ustinova, EE and Schultz, HD. Activation of cardiac vagal afferents in ischemia and reperfusion. Prostaglandins versus oxygen-derived free radicals. Circ Res. 74(5):904-11, 1994. PMID: 8156637
  • Ding, Y, Li, YL and Schultz, HD. Role of blood flow in carotid body chemoreflex function in heart failure. J Physiol. 589(Pt 1):245-58, 2011. PMCID: PMC3039273.
  • Marcus NJ, Del Rio R, Ding Y, Schultz HD. KLF2 mediates enhanced chemoreflex sensitivity, disordered breathing and autonomic dysregulation in heart failure. J Physiol. 596(15):3171-3185, 2018. doi: 10.1113/JP273805. PMCID: PMC6068211

Full list of publications, Scopus

Honors and Service
  • Fellow of the American Physiological Society, 2017-present
  • Senior editor, Journal of Physiology, 2016-present
  • UNMC Distinguished Scientist Award, 2014
  • President, Nebraska Physiological Society, 2006, 2018
  • Fellow of the Councils for Circulation and for High Blood Pressure Research, American Heart Association, 1995-present
  • Joseph P. Gilmore, Ph.D., Distinguished Basic Scientist Award, University of Nebraska Medical Center College of Medicine,1993
  • Established Investigator, American Heart Association, 1990 - 1995
  • James Scholar, Phi Beta Kappa, University of Illinois, 1972 - 1974