UNMC_Acronym_Vert_sm_4c
University of Nebraska Medical Center

Publications

Selected Publications

  1. Luo Z, Wan Z, Ren P, Zhang B, Huang H, Zhang Z, Chen Y, Huang Y, Wang J, Li S*, Sun J*. In situ Formation of Fibronectin-Enriched Protein Corona on Epigenetic Nanocarrier for Enhanced Synthetic Lethal Therapy. Advanced Science, 2024, 2307940. (Corresponding author)
  2. Luo Z, Huang Y, Batra N, Chen Y, Huang H, Wang Y, Zhang Z, Li S, Chen C, Wang Z, Sun J, Wang Q, Yang D, Lu B, Conway J, Li L, Yu A, Li S*. Inhibition of iRhom1 by CD44-targeting nanocarrier for improved cancer immunochemotherapy. Nature Communications, 2024, 15, 255.
  3. Chen Y, Huang Y, Li Q, Luo Z, Zhang Z, Huang H, Sun J, Zhang L, Sun R, Bain D, Conway J, Lu B*, Li S*. Targeting Xkr8 via nanoparticles-mediated in situ codelivery of siRNA and chemotherapy drugs for cancer immunochemotherapy. Nature Nanotechnology, 2023, 18, 193-204.
  4. Wan Z, Huang H, Zhang M, Zhang B, Cai X, Zhang Z, Luo Z, Chen Y, Zhang Y, Xie W, Yang D, Wang J, Li S*, Sun J*. Overcoming Pancreatic Cancer Immune Resistance by Codelivery of CCR2 Antagonist Using a STING-Activating Gemcitabine-Based Nanocarrier. Materials Today, 2023, 62, 33-50. (Corresponding author)
  5. Moharil P, Wan Z, Pardeshi A, Li J, Huang H, Luo Z, Rathod S, Zhang Z, Chen Y, Zhang B, Fernandez C, Sun J*, Li S*. Engineering a folic acid-decorated ultrasmall gemcitabine nanocarrier for breast cancer therapy: Dual targeting of tumor cells and tumor-associated macrophages. Acta Pharmaceutica Sinica B, 2022, 12, 1148-1162. (Co-Corresponding author)
  6. Kumar S, Das S, Sun J, Huang Y, Singh SK, Srivastava P, Sondarva G, Nair RS, Viswakarma N, Ganesh B, Duan L, Maki CG, Hoskins K, Danciu O, Rana B, Li S, Rana A*. Mixed lineage kinase 3 and CD70 cooperation sensitize trastuzumab-resistant HER2+ breast cancer by ceramide-loaded nanoparticles. Proceedings of the National Academy of Sciences, 2022, 119, e2205454119.
  7. Wan Z, Sun R, Liu YW, Li S, Sun J, Li J, Zhu J, Moharil P, Zhang B, Ren P, Ren G, Zhang M, Ma X, Dai S, Yang D, Lu B, Li S*. Targeting metabotropic glutamate receptor 4 for cancer immunotherapy. Science Advances, 2021, 7, eabj4226.
  8. Sun J*, Wan Z, Xu J, Luo Z, Ren P, Zhang B, Diao D, Huang Y, Li S*. Tumor size-dependent abscopal effect of polydopamine-coated all-in-one nanoparticles for immunochemo-photothermal therapy of early- and late-stage metastatic cancer. Biomaterials, 2021, 269, 120629.
  9. Sun J*, Chen Y, Xu J, Song X, Wan Z, Du Y, Ma W, Li X, Zhang L, Li S*. High loading of hydrophobic and hydrophilic agents via small immunostimulatory carrier for enhanced tumor penetration and combinational therapy. Theranostics. 2020, 10, 1136-1150.
  10. Sun J*, Wan Z, Chen Y, Xu J, Luo Z, Parise RA, Diao D, Ren P, Beumer JH, Lu B, Li S*. Triple drugs co-delivered by a small gemcitabine-based carrier for pancreatic cancer immunochemotherapy. Acta Biomaterialia, 2020, 106, 289-300.
  11. Liu Y, Sun J, Huang Y, Chen Y, Li J, Liang L, Xu J, Wan Z, Zhang B, Li Z, Li S*. Metformin-conjugated micellar system with intratumoral pH responsive de-shielding for co-delivery of doxorubicin and nucleic acid. Biochemical Pharmacology, 2021, 114453. (co-first author)
  12. Ma W., Sun J., Xu J., Luo Z., Diao D., Zhang Z., Oberly JP, Minnigh M, Xie W, Poloyac S, Huang Y, Li S*. Sensitizing triple negative breast cancer to tamoxifen chemotherapy via a redox-responsive vorinostat-containing polymeric prodrug nanocarrier. Theranostics. 2020, 10, 2463-2478. (co-first author)
  13. Xu J, Sun J, Ho PY, Luo Z, Ma W, Zhao W, Rathod S, Fernandez C, Venkataramanan R, Xie W, Yu AM, Li S*. Creatine based polymer for codelivery of bioengineered MicroRNA and chemodrugs against breast cancer lung metastasis. Biomaterials. 2019, 210, 25-40. (Co-first author)
  14. Chen Y, Sun J, Huang Y, Liu Y, Liang L, Yang D, Lu B, Li S* Targeted Codelivery of Doxorubicin and IL-36γ Expression Plasmid for An Optimal Chemo-Gene Combination Therapy against Cancer Lung Metastasis. Nanomedicine: Nanotechnology, Biology, and Medicine. 2019, 15, 129-141. (Co-first author)
  15. Chen Y, Sun J, Huang Y, Lu B, Li S* Improved Cancer Immunochemotherapy via Optimal Co-delivery of Chemotherapeutic and Immunomodulatory Agents. Molecular pharmaceutics. 2018, 15, 5162-5173. (Co-first author)
  16. Sun J, Sun L, Li J, Xu J, Wan Z, Ouyang Z, Liang L, Li S*, Zeng D* A Multi-Functional Polymeric Carrier for Simultaneous Positron Emission Tomography Imaging and Combination Therapy. Acta biomaterialia, 2018, 75, 312-322.
  17. Sun J, Wang Z, Cao A, Sheng R. Synthesis of crosslinkable diblock terpolymers PDPA-b-P (NMS-co-OEG) and preparation of shell-crosslinked pH/redox-dual responsive micelles as smart nanomaterials. RSC advances,2019, 9, 34535-34546.
  18. Sun J, Liu Y, Chen Y, Zhao W, Zhai Q, Rathod S, Huang Y, Tang S, Kwon Y, Fernandez C, Venkataramanan R, Li S*. Doxorubicin delivered by a redox-responsive dasatinib-containing polymeric prodrug carrier for combination therapy. Control. Release, 2017, 258, 43-55.
  19. Sun J, Chen Y, Huang Y, Zhao W, Liu Y, Venkataramanan R, Lu B, Li S*. Programmable co-delivery of the immune checkpoint inhibitor NLG919 and chemotherapeutic doxorubicin via a redox-responsive immunostimulatory polymeric prodrug carrier. Acta Pharmacol Sin. 2017, 38, 823-834.
  20. Sun J, Chen Y, Li K, Huang Y, Zhang X, Zhao W, Wei Y, Xu L, Venkataramanan R, Li S*. A prodrug micellar carrier assembled from polymers with pendant farnesyl thiosalicylic acid moieties for improved delivery of paclitaxel. Acta Biomaterialia, 2016, 43, 282-291.
  21. Sun J, Sheng R, Luo T, Wang Z, Li H, Cao A*. Synthesis of Diblock/Statistical Cationic Glycopolymers with Pendant Galactose and Lysine Moieties: Gene Delivery Application and Intracellular Behaviors. Journal of Materials Chemistry B, 2016, 4, 4696-4706.
  22. Sun J, Luo T, Sheng R, Li H, Wang Z, Cao A*. Intracellular plasmid DNA delivery by self-assembled nanoparticles of amphiphilic PHML-b-PLLA-b-PHML copolymers and the endocytosis pathway analysis. Journal of biomaterials applications. 2016, 31, 606-621.
  23. Sun J, Luo T, Sheng R, Li H, Cao A*. Preparation of functional water-soluble low-cytotoxic poly(methacrylate)s with pendant cationic L-Lysines for efficient gene delivery. Macromolecular Bioscience, 2013, 13, 35-47.
  24. Sun J, Luo T, Sheng R, Cao A*. Preparation of cationic l-lysine conjugated poly(2-hydroxyethyl methacrylate)s and their potential application as low cytotoxic efficient gene delivery vectors. Control. Release, 2013, 172, Pages e108.

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