Shilpa Buch, PhD
Professor, UNMC Department of Pharmacology and Experimental Neuroscience
Director, UNMC Center for Substance Abuse Research
Education
- PhD, University of Baroda, India, 1982
- MS in Microbiology, University of Baroda, India, 1979
Memberships
- Society on NeuroImmune Pharmacology
- International Society of Neurovirology
- International Society for Extracellular Vesicles
- Nebraska Center for Substance Abuse Research
- Indian Academy of Neurosciences
- American Society for Exosomes and Microvesicles
- American Association for Extracellular Vesicles
- International Brain Research Organization
- International Drug & Alcohol Research Society
- American Society Intercellular Communication
Recognition
- 2023 Distinguished Services Award, Society on NeuroImmune Pharmacology,
- 2017 Herman Friedman Founders Award, Society on NeuroImmune Pharmacology.
- 2016 Community Pride of Nebraska Professor of Neuroscience.
- 2016 International Society of Neurovirology Women in Neuroscience Award.
- 2015 UNMC Scientist Laureate.
- 2013 Distinguished Services Award, Society on NeuroImmune Pharmacology.
- 2012 Wybran Award, Society on NeuroImmune Pharmacology.
- 2011 UNMC Distinguished Scientist Award.
- 2008 UNMC Research Investigator Award.
- 2005 K-INBRE Faculty Scholar Award.
Selected Publications
- Kannan M, Sil S, Oladapo A, Thangaraj A, Periyasamy P, Buch S. HIV-1 Tat-mediated microglial ferroptosis involves the miR-204-ACSL4 signaling axis. Redox Biol. 2023;62:102689. PubMed PMID: 37023693; PMCID: PMC10106521.
- Chemparathy DT, Sil S, Callen S, Chand HS, Sopori M, Wyatt TA, Acharya A, Byrareddy SN, Fox HS, Buch S. Inflammation-Associated Lung Tissue Remodeling and Fibrosis in Morphine-Dependent SIV-Infected Macaques. Am J Pathol. 2023;193(4):380-91. PubMed PMID: 37003622; PMCID: PMC10116601.
- Chivero ET, Thangaraj A, Tripathi A, Periyasamy P, Guo ML, Buch S. NLRP3 Inflammasome Blockade Reduces Cocaine-Induced Microglial Activation and Neuroinflammation. Mol Neurobiol. 2021;58(5):2215-30. PubMed PMID: 33417223; PMCID: PMC8026688.
- Thangaraj A, Chivero ET, Tripathi A, Singh S, Niu F, Guo ML, Pillai P, Periyasamy P, Buch S. HIV TAT-mediated microglial senescence: Role of SIRT3-dependent mitochondrial oxidative stress. Redox Biol. 2021;40:101843. PubMed PMID: 33385630; PMCID: PMC7779826.
- Sil S, Hu G, Liao K, Niu F, Callen S, Periyasamy P, Fox HS, Buch S. HIV-1 Tat-mediated astrocytic amyloidosis involves the HIF-1α/lncRNA BACE1-AS axis. PLoS Biol. 2020;18(5):e3000660. PubMed PMID: 32453744; PMCID: PMC7274476.
- Liao K, Niu F, Hu G, Yang L, Dallon B, Villarreal D, Buch S. Morphine-mediated release of miR-138 in astrocyte-derived extracellular vesicles promotes microglial activation. J Extracell Vesicles. 2020;10(1):e12027. PubMed PMID: 33304479; PMCID: PMC7710131.