Tissue Procurement Shared Resource
Among the most valuable resources to our investigators is human tissue for use in basic science, translational, and clinical studies, and clinical trials.
The mission of the UNMC Tissue Procurement Shared Resource is to procure and coordinate distribution of fresh frozen human tissue in an optimal state of preservation for requesting investigators without impacting diagnostic quality, accuracy and safety in anatomic pathology. Additional services offered include biospecimen DNA or RNA extraction, sectioning of frozen tissues, short-term tissue culture, cytogenetic/molecular cytogenetic analysis, and tissue preparation via investigator-driven protocols.
Dr. Kurt Fisher is the director of the facility. A multidisciplinary oversight committee reviews tissue requests to prioritize and ensure equitable usage. The facility requires proper Institutional Review Board approval prior to release of human tissues for research purposes. The facility is staffed by highly skilled technologists with expertise in pathology, cytogenetics, and molecular biology. The facility can provide basic demographic and histopathologic information on samples through a confidential database so that findings from basic research can be correlated with clinical data while maintaining strict patient confidentiality.
For Basic Science and Translational Research
Acquisition: At the time of surgery
Facility: Pathology department or frozen section laboratory
Requirements:
- Approved IRB protocol of study
- Contact technical staff
- Research Coordinator: Artem Pachikov
- Lead Pathology Assistant: Travis Rinehart
- Clearance by the service director, Dr. Kurt Fisher
Facility: Tissue Procurement Shared Resource/Frozen Tissue Bank
Primary Technical Contact: Yimin Sun
Facility: UNMC Paraffin Tissue Bank
Requirements:
- Approved IRB protocol of study or exemption documentation
- Contact technical staff
- Research Coordinator: Artem Pachikov
Facility: Slide Room/Histology
Requirements:
- Cases must be >2 years old
- Collaborate with a UNMC pathologist on study
- Approved IRB protocol of study or exemption documentation
- Contact technical staff
- Research Coordinator: Artem Pachikov
- Reference Personnel: Debhora Hamler
- Clearance by the service director, Dr. Kurt Fisher
For Clinical Trials
Acquisition: At time of surgery
Facility: Pathology department or frozen section laboratory
Requirements:
- Completion of clinical trials request form
- Approved IRB protocol of study
- Contact technical staff
- Research Coordinator: Artem Pachikov
- Meeting with pathology staff prior to procedure(s) to coordinate logistics
- Clearance by the service director, Dr. Kurt Fisher
Purpose: To be sent to external institutions
Facility: Slide Room/Histology
Requirements:
- Prior approval from the service director, Dr. Kurt Fisher
- Completion of clinical trials request form
- Approved IRB protocol of study
- Provide cost center associated with IRB for charges
Technical Staff:
- Research Coordinator: Artem Pachikov
- Reference Personnel: Debhora Hamler
Kurt W. Fisher, MD, PhD
Assistant Professor, UNMC Department of Pathology, Microbiology and Immunology
Director, UNMC Tissue Procurement Shared Resource Bank, Fred and Pamela Buffett Cancer Center & Department of Pathology
Fred & Pamela Buffett Cancer Center, Full Member