Fey Laboratory
Biofilms and Amino Acids
Vice Chair of Research, UNMC Department of Pathology, Microbiology and Immunology
Professor
Associate Director, UNMC Center for Staphylococcal Research
Staphylococcus aureus and S. epidermidis are highly significant causes of community and hospital acquired infections. Currently, the two major themes in the research laboratory of Dr Fey include the function and relevance of biofilm accumulation molecules in Staphylococcus epidermidis including polysaccharide intercellular adhesin and accumulation-associated protein. Secondly, we are investigating amino acid metabolism and the importance of the use of amino acids as carbon sources in an in vivo environment.
We work in close collaboration with investigators at the Center for Staphylococcal Research in the Department of Pathology, Microbiology and Immunology and Division of Infectious Disease investigating multiple aspects of biofilm formation, bacterial metabolism, pathogenesis and the host response.
Dr. Fey serves as medical director of the Nebraska Medical Center Clinical Microbiology Laboratory. This work has afforded our laboratory great insight into relevant questions related to infectious disease and bacterial pathogenesis including mechanisms of antibiotic resistance.
Teaching
Dr. Fey is current course coordinator for the following:
- PAMM 871: Antibiotics-Mechanisms of Action and Resistance
- PAMM 910: Bacterial Pathogenesis
PhD students typically take the following courses during their tenure in the Fey laboratory.
- IPBS 801 - Fundamentals of Biomolecules
- PBS 802 - Molecular Cell Biology
- IPBS 803 - Fundamentals of Receptors & Cell Signaling
- PAMM 857: Introductory Immunobiology
- PAMM 898: Bacterial Genetics
- PAMM 910: Bacterial Pathogenesis
- PAMM 950: Topics in Bacterial Physiology and metabolism
- BIOS 816: Biostatistical Methods 1
- PAMM 992: Advanced Topics in Immunology, Pathology and Infectious Disease.
The Center for Staphylococcal Research has a weekly journal club
Electives
- PAMM 871: Antibiotics: Mechanisms of Action and Resistance
- PAMM 890: The Molecular Biology of Viruses
- PAMM 955 Advanced Immunology