Caroline Ng, PhD
Associate Professor, UNMC Department of Pathology, Microbiology and Immunology
Affiliate Faculty, UNMC Global Center for Health Security
Caroline Ng, PhD, is an associate professor in the UNMC Department of Pathology, Microbiology and Immunology. She also serves as affiliate faculty in the UNMC Global Center for Health Security and holds a courtesy faculty appointment as an assistant professor in the University of Nebraska Omaha Department of Biology.
She studies the role of parasite proteostasis in artemisinin resistance.
Dr. Ng grew up in Malaysia, a country that still experiences deaths due to infectious diseases, including malaria. Her lived experiences have created a desire to alleviate human suffering from infectious diseases.
She has a longstanding interest in the concept of proteostasis. For her PhD thesis, she utilized the human cytomegalovirus protein US2 as a tool to interrogate endoplasmic reticulum associated degradation and identified a molecular component of the dislocation complex by mass spectrometry and biochemical methods. For her postdoctoral training, she worked on understanding drug resistance in malaria.
As an associate research scientist at Columbia University, she examined the role of proteasomes in artemisinin resistance.
- BA: Biology, cum laude, Barnard College of Columbia University.
- PhD: Biomedical sciences, Mount Sinai School of Medicine.
- Postdoctoral training: Columbia University Medical Center.
The Ng lab is interested in understanding the genetics and molecular mechanisms underlying antimalarial drug resistance, as well as discovering novel therapeutic targets and/or pathways. In particular, we are interested in how ubiquitin, the ubiquitin-proteasome system, and other degradative systems affect parasite drug responses and malaria pathogenesis.
- Keynote speaker, early career, First Women in Malaria conference, 2021.
- UNMC New Investigator Award, 2018.
- Mensa member.
- American Chemical Society
- American Society of Tropical Medicine and Hygiene