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Research highlights

Howard Fox, M.D., Ph.D.

UNMC College of Medicine faculty received 14 grant awards representing more than $1.4 million in new funding during the month of February. 

The following industry-sponsored contracts and foundation grants were received.  Information on clinical trials enrolling patients at UNMC can be found here.

Industry-sponsored grants:

Ronald Zolty, M.D., Ph.D., internal medicine – cardiology, is the UNMC lead on a study on the effects of in-hospital initiation of a new treatment in patients who were stabilized following hospitalization for acute decompensated heart failure and reduced ejection fraction. Dr. Zolty also received support to develop an observational registry of treatment patterns in U.S. heart failure patients with reduced ejection fraction.

Fedja Rochling, M.B.B.C.H., internal medicine – GI, is the UNMC lead on a longitudinal observational study of patients with primary biliary cholangitis.

Rana Zabad, M.D., neurological sciences, is the UNMC lead on a study of a novel antibody as a treatment in patients with primary progressive multiple sclerosis. Dr. Zabad is also the UNMC lead in a retrospective study of the clinical, neurological, tolerability, and safety outcomes of patients who received certain treatments for multiple sclerosis.

Troy Plumb, M.D., internal medicine – nephrology, is the UNMC lead on a study of a new hemodialysis system that will be evaluated both in-center and in-home by patients with end-stage renal disease.

Kathleen Grant, M.D., internal medicine – pulmonary, has received support through the Palo Alto Institute for Research and Education to assist in a study that will examine the effectiveness of Alcoholics Anonymous Intensive Referral with concerned others (i.e. family, friends, caretakers) of individuals in treatment for alcohol use disorders.

Austin Thompson, M.D., internal medicine – pulmonary, is the UNMC lead of a clinical trial to evaluate the safety and efficacy of a novel inhaled treatment for patients with pulmonary hypertension. Dr. Thompson is also the UNMC lead on an additional version of this trial, which will look specifically at a subset of patients with pulmonary hypertension due to parenchymal lung disease.

Howard Fox, M.D., Ph.D., pharmacology and experimental neuroscience, has received support from Drexel University to assist in a study that will examine the mechanisms of dopamine-mediated increase in HIV infection of macrophages.

Wallace Thoreson, Ph.D., ophthalmology and visual sciences, has received support from Indiana Wesleyan University to assist on their National Science Foundation grant that aims to understand the role of extracellular hydrogen ions in processing visual signals.

Andre Kalil, M.D., internal medicine – infectious diseases, has received support through Duke University’s Antibacterial Resistance Leadership Group to assist in a study on gram-negative bacteria and lung pharmacokinetics.

Shelby Kutty, M.D., Ph.D., pediatrics – cardiology, has received support from the Children's Hospital & Medical Center Foundation for a study titled "Inhibition of Drp1 Improves Diastolic Function in a Porcine Model of Right Ventricular Ischemia-Reperfusion Injury."

Shailender Singh, M.B.B.S., internal medicine – GI, has received support from the University of Pittsburgh to assist in their development of a Pancreatic Cystic Reference Set, which is designed to evaluate biomarkers to create a standard method for determining whether a patient would benefit from surgical resection of their cystic lesion.

1 comment

  1. Kathleen Healey says:

    Dr. Zabad good for you it's about time somebody focuses on the progressive part of multiple sclerosis this is extremely promising research that you are doing.

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