The UNMC College of Medicine received grant and funding awards representing more than $7 million in new funding in September. Awards included:
Bin Duan, PhD, internal medicine-cardiovascular, received a grant of $750,000 from the American Heart Association for an analysis of plasma derived sEVs by combining SERS spectroscopy and machine learning for CAD diagnosis and prognosis.
Hanjun Wang, MD, anesthesiology, received a grant of $741,512 from DHHS/NIH/NHLBI for a study on stellate ganglia Nrf2 signaling and enhanced cardiac sympathetic tone in chronic heart failure.
Siddappa Byrareddy, PhD, pharmacology and experimental neuroscience, received a grant of $690,750 from the DHHS/NIH/NIDA for a study on sex differences in modulating HIV/SIV reservoirs in the context of opioid.
Kurt Fisher, MD, PhD, pathology, microbiology and immunology, received a grant of $439,367 from DHHS/NIH/NCI for an assessment of strategies for targeting transcriptional co-activators in colorectal cancer.
Prasanta Dash, PhD, pharmacology and experimental neuroscience, received a grant of $383,750 from DHHS/NIH/NIA for a study exploring the molecular, neuro-immune and behavioral changes during HIV-associated progressive aging using a long-term humanized mice model.
Saraswathi Vishwanathan, PhD, internal medicine-DEM, received a grant of $374,081 from the DHHS/NIH/NIAAA for the study “Redox Signaling and AMPK Crosstalk on Alcohol-Induced Multi-Organ Damage: Liver and Adipose Tissue.”
Karsten Bartels, MD, PhD, anesthesiology, received a grant of $330,829 from DHHS/NIH/NIAAA for the study “Leveraging Alcohol Use Disorder Screening for Treatment in Routine Perioperative Care.”
Channabasavvaiah Gurumurthy, PhD, genetics, cell biology and anatomy, received a grant of $330,025 from DHHS/NIH/NIGMS for “Prototype Mouse Models for SEND-Based mRNA Delivery and Technology Development.”
Shibiao Wan, PhD, genetics, cell biology and anatomy, received a grant of $307,000 from DHHS/NIH/Office of the Director for a study on leveraging heterogenous common fund data sets and beyond for identifying lung cancer subtypes.
Arpan Acharya, PhD, pharmacology and experimental neuroscience, received a grant of $300,000 from DHHS/NIH/Office of the Director for a study on SIV reservoirs dynamics during aging.
Steven Yeh, MD, ophthalmology and visual sciences, received a grant of $247,932 from Emory University for COVID-19 Eye substudy in the RECOVER consortium. Dr. Yeh also received a grant of $50,000 from the Retina Society for the study “Molecular and immunologic mechanisms of HIV- and non-HIV-related CMV retinitis: A global approach to disease understanding.”
Keshore Bidasee, PhD, pharmacology and experimental neuroscience, received a grant of $230,250 from DHHS/NIH/NINDS for a study exploring neurological disorders in HIV-1 infection.
Lisa Rucks, PhD, pathology, microbiology and immunology, received a grant of $207,225 from DHHS/NIH/NIAID for the study “Chlamydia trachomatis manipulates (PI)CALM to carry on.”
Kelly Stauch, PhD, neurological sciences, received a grant of $200,000 from the Alzheimer’s Association for the study “The Role of APOE4 in Synaptic Mitochondrial Dysfunction.”
Peter Murphy, MD, internal medicine-pulmonary, received a grant of $186,910 from the Cystic Fibrosis Foundation for the CFF Center Adult Program.
Joseph Americo Fernandes, MD, neurological sciences, received a grant of $183,733 from Massachusetts General Hospital for the “Master Agreement: ALL ALS East – ALL ALS Consortium Project.”
Christopher Barrett, MD, surgery-acute care, received a grant of $120,096 from DHHS/NIH/NHLBI for a study of mechanisms of complement activation in traumatic injury.
Cyrus Desouza, MBBS, internal medicine-DEM, received a grant of $66,482 from the Nebraska Educational Biomedical Research Foundation as the Nebraska ICA for Reagan TeKolste. Dr. DeSouza also received a grant of $43,422 from the Nebraska Educational Biomedical Research Foundation as the Nebraska ICA for Susan Burbach, and a grant of $22,759 from the Nebraska Educational Biomedical Research Foundation as the Nebraska ICA for Ally Thavenet.
Sara Bares, MD, internal medicine-infectious diseases, received a grant of $30,987 from Massachusetts General Hospital for “EMPOWHer: Embracing Midlife & Menopause Positively-Offerings by Women with HIV.”
Shan Fan, MD, ophthalmology and visual sciences, received a grant of $22,677 from the University of Georgia for a study on the effect of suprachoroidal space hydrogel injection on aqueous humor dynamics.
Sidharth Mahapatra, MD, PhD, pediatrics-critical care, received a grant of $17,192 from the University of Pennsylvania for PROSpect – Prone and Oscillation Pediatric Clinical Trial.
Iraklis Pipinos, MD, surgery-vascular surgery, received a grant of $16,544 from the University of Nebraska at Omaha for “Collaborative Research: Detecting Gait Phases with Raised Metabolic Cost using Robotic Perturbations and System Identification for Enabling Targeted Rehabilitation Therapy.”
Erica Stohs, MD, internal medicine-infectious diseases, received a grant of $16,059 from the University of Washington for a study of cytomegalovirus (CMV) vaccine in orthotopic liver transplant candidates.
Carol Casey, PhD, internal medicine-GI, received a grant of $15,629 from the University of Nebraska-Lincoln for the Nebraska Center for the Prevention of Obesity Diseases through Dietary Molecules.
Ram Subramanyan, MD, PhD, surgery-cardiothoracic surgery, received a grant of $4,000 from the New England Research Institutes for comparison of methods of pulmonary blood flow augmentation in neonates: Shunt vs. stent.
Industry-sponsored grants and contracts:
The following industry-sponsored grants and contracts were received.
Omar Abughanimeh, MBBS, internal medicine-oncology/hematology, received funding for a study to evaluate novel immunotherapy combinations as first-line treatment in participants with recurrent/metastatic PD-L1 positive squamous cell carcinoma of the head and neck.
Sookyong Koh, MD, PhD, pediatrics-neurology, received funding for a trial of EPX-100 (Clemizole Hydrochloride) as adjunctive therapy in children and adult participants with Dravet syndrome.
Laura Graeff-Armas, MD, PhD, internal medicine-DEM, received funding for a trial to evaluate the safety, pharmacokinetics and efficacy of MBX 2109 in patients with hypoparathyroidism
Sarah Lonowski, MD, dermatology, received funding for a trial to evaluate the efficacy and safety of Anifrolumab in adults with chronic and/or subacute cutaneous lupus erythematosus.
Ashley Deschamp, MD, pediatrics-pulmonary, received funding for “A Natural History Study of Exocrine Pancreatic Function in Infants With Cystic Fibrosis Less Than 12 Months of Age.”
Scott Koepsell, MD, PhD, pathology, microbiology and immunology, received funding for a study of HemosIL CL ADAMTS13 activity on the ACL TOP 970 CL and/or HemosIL AcuStar ADAMTS13 activity on the ACL AcuStar Protocol – sample collection.