Department faculty have been awarded two grants. In addition, our researchers’ work has generated 30 manuscript publications.
New grants
PI: Scott Koepsell MD
Support of the studies and procedures to be performed to support standardization of the Teucer’s Podocin RT-qPCR assay. Teucer Biotech Inc.
PI: Joshua Santarpia PhD
Octopus FY24. National Strategic Research Institute
Publications (November 2024-current):
Tetracycline and Oxacillin Act Synergistically on Biofilms and Display Increased Efficacy In Vivo Against Staphylococcus aureus. Tooke AK, Hodges RE, Pyrah JF, Bayles KW, Renshaw SA, Foster SJ. Curr Microbiol. 2024 Nov 6;81(12):447. doi: 10.1007/s00284-024-03959-4. PMID: 39505760
EBV-positive HIV-associated diffuse large B cell lymphomas are characterized by JAK/STAT (STAT3) pathway mutations and unique clinicopathologic features. Chapman JR, Bouska AC, Zhang W, Alderuccio JP, Lossos IS, Rimsza LM, Maguire A, Yi S, Chan WC, Vega F, Song JY. Br J Haematol. 2021 Sep;194(5):870-878. doi: 10.1111/bjh.17708. Epub 2021 Jul 17. PMID: 34272731
Myxoid “pauci-hemosiderotic” fibrolipomatous tumour: a diagnostic challenge. O’Connor P, Bridge JA, Meis JM, Cloutier JM. Histopathology. 2024 Sep 9. doi: 10.1111/his.15317. Online ahead of print. PMID: 39252432
DEK::AFF2 Fusion-Associated Squamous Cell Carcinoma: A Case Series with Literature Review on an Emerging and Challenging Entity. Amin SE, Lewis JS Jr, Bridge JA, Hang JF, Naik U, Bishop JA, Saluja K. Head Neck Pathol. 2024 Sep 23;18(1):86. doi: 10.1007/s12105-024-01690-x. PMID: 39312022
Myoid Hamartoma of the Breast With HMGA2 Rearrangement and Associated In-Situ and Invasive Carcinoma: Case Report and Review of Literature. Sta Ines FMG, Marketkar S, Ng S, Manrai P, James Sung C, Bridge JA, Singh K. Int J Surg Pathol. 2024 Oct 29:10668969241271420. doi: 10.1177/10668969241271420. Online ahead of print. PMID: 39471995
Chlamydia trachomatis modulates the expression of JAK-STAT signaling components to attenuate the type II interferon response of epithelial cells. Fontanilla FL, Ibana JA, Carabeo RA, Brinkworth AJ. mBio. 2024 Oct 16;15(10):e0183424. doi: 10.1128/mbio.01834-24. Epub 2024 Aug 28. PMID: 39194253
Feasibility Assessment of a Novel Isolation Care Tent in Uganda During the 2022 Sudan ebolavirus Outbreak. Broadhurst MJ, Ayebare RR, Brett-Major DM, Carroll SM, Lacore J, Laskey AD, Lawler JV, Lord P, Vazquez RM, Waitt P, Lamorde M. Health Secur. 2024 Sep;22(S1):S86-S96. doi: 10.1089/hs.2023.0177. Epub 2024 Aug 13. PMID: 39137059
Reach, Adoption, Implementation, and Sustainability of the Mobile Health for Migrant Health (mHealth-4-Mhealth) Program: Nebraska, 2022-2023. McCulloh RJ, Kerns E, Abresch C, Warren M, Sanchez F, Marfileno G, Rivera L, Broadhurst MJ. Am J Public Health. 2024 Nov;114(11):1212-1216. doi: 10.2105/AJPH.2024.307746. Epub 2024 Aug 22. PMID: 39173092
Single-cell profiling reveals a conserved role for hypoxia-inducible factor signaling during human craniotomy infection. Van Roy Z, Kak G, Korshoj LE, Menousek JP, Heim CE, Fallet RW, Campbell JR, Geary CR, Liu B, Gorantla S, Poluektova LY, Duan B, Campbell WS, Thorell WE, Kielian T. Cell Rep Med. 2024 Oct 15:101790. doi: 10.1016/j.xcrm.2024.101790. Online ahead of print. PMID: 39426374
The genotypic antibiogram: using gram-negative antimicrobial resistance genes identified via rapid blood culture identification tests to optimize treatment of Enterobacterales bloodstream infections. Sunagawa SW, Tigh J, Chan YA, Okada A, Bergman SJ, Van Schooneveld TC, Fey PD, Ryder JH. Antimicrob Steward Healthc Epidemiol. 2024 Oct 14;4(1):e172. doi: 10.1017/ash.2024.406. eCollection 2024. PMID: 39411659
Efficacy and Possible Mechanism(s) of Action of Gallium Tetraphenylporphyrin Nanoparticles against HIV-TB Coinfection in an In Vitro Granuloma Structure Model. Choi SR, Kulkarni S, Arnett E, Schlesinger LS, Britigan BE, Narayanasamy P. ACS Infect Dis. 2024 Nov 5. doi: 10.1021/acsinfecdis.4c00639. Online ahead of print. PMID: 39499869
Clofazimine inhibits small-cell lung cancer progression by modulating the kynurenine/aryl hydrocarbon receptor axis. Sharma G, Abdullah KM, Qais FA, Khan P, Cox JL, Sarwar T, Nasser MW, Batra SK, Siddiqui JA. Int J Biol Macromol. 2024 Oct 26:136921. doi: 10.1016/j.ijbiomac.2024.136921. Online ahead of print. PMID: 39490481
Inulin-based nanoparticles for targeted siRNA delivery in acute kidney injury. Jogdeo CM, Panja S, Kumari N, Tang W, Kapoor E, Siddhanta K, Das A, Boesen EI, Foster KW, Oupický D. J Control Release. 2024 Oct 24;376:577-592. doi: 10.1016/j.jconrel.2024.10.027. Online ahead of print. PMID: 39419450
Applying a DEI-HE Lens to Your Laboratory. Auen T, Brice L, Tikhonov A, Wang J, Fyffe-Freil R. J Appl Lab Med. 2024 Nov 4;9(6):1110-1112. doi: 10.1093/jalm/jfae074. PMID: 39489487
Body Mass Index and Postacute Sequelae of SARS-CoV-2 Infection in Children and Young Adults. Zhou T, Zhang B, Zhang D, Wu Q, Chen J, Li L, Lu Y, Becich MJ, Blecker S, Chilukuri N, Chrischilles EA, Chu H, Corsino L, Geary CR, Hornig M, Hornig-Rohan MM, Kim S, Liebovitz DM, Lorman V, Luo C, Morizono H, Mosa ASM, Pajor NM, Rao S, Razzaghi H, Suresh S, Tedla YG, Utset LV, Wang Y, Williams DA, Witvliet MG, Mangarelli C, Jhaveri R, Forrest CB, Chen Y. JAMA Netw Open. 2024 Oct 1;7(10):e2441970. doi: 10.1001/jamanetworkopen.2024.41970. PMID: 39466241
Positive Airway Pressure, Mortality, and Cardiovascular Risk in Older Adults With Sleep Apnea. Mazzotti DR, Waitman LR, Miller J, Sundar KM, Stewart NH, Gozal D, Song X; Greater Plains Collaborative (Geary CR). JAMA Netw Open. 2024 Sep 3;7(9):e2432468.doi:10.1001/jamanetworkopen.2024.32468. PMID: 39259540
Refining Diagnostic Subtypes of Peripheral T-cell Lymphoma Using a Multiparameter Approach. Amador C, Weisenburger DD, Gomez A, Bouska A, Alshomrani A, Sharma S, Shah R, Greiner TC, Vega F, Rosenwald A, Ott G, Feldman AL, Jaffe ES, Ozkaya N, Ondrejka SL, Cook JR, Raess PW, Savage KJ, Slack GW, Song JY, Scott DW, Campo E, Rimsza LM, Khoury JD, Staudt LM, Chan WC, Iqbal J; A Leukemia and Lymphoma Molecular Profiling Project (LLMPP) Consortium. Mod Pathol. 2024 Nov 2:100646. doi: 10.1016/j.modpat.2024.100646. Online ahead of print. PMID: 39491745
Can molecular patterns help to classify overlapping entities in myeloid neoplasms? Hoermann G, Khoury JD. Histopathology. 2024 Oct 21. doi: 10.1111/his.15339. Online ahead of print. PMID: 39428913
Tissue niche influences immune and metabolic profiles to Staphylococcus aureus biofilm infection. Van Roy Z, Arumugam P, Bertrand BP, Shinde DD, Thomas VC, Kielian T. Nat Commun. 2024 Oct 17;15(1):8965. doi: 10.1038/s41467-024-53353-8. PMID: 39420209
Examining Differences by Sex in Dermatofibrosarcoma Protuberans Patients: An Analysis of 7,839 Cases From the 2000 to 2020 Surveillance, Epidemiology, and End Results Database. Taylor MA, Ituarte BE, Thomas SI, Fernandez JM, Lauer SR, Wysong A. Dermatol Surg. 2024 Nov 1;50(11):1071-1073. doi: 10.1097/DSS.0000000000004254. Epub 2024 Jun 6. PMID: 38843458
A Rare Case of Giant Cystic Adenomatoid Tumor of the Uterus With Literature Review. Renavikar PS, Adwer L, Wagner DG, Lele SM. Case Rep Obstet Gynecol. 2024 Oct 23;2024:7791245. doi: 10.1155/2024/7791245. eCollection 2024. PMID: 39479461
Enhanced cell stress response and protein degradation capacity underlie artemisinin resistance in Plasmodium falciparum. Rosenthal MR, Vijayrajratnam S, Firestone TM, Ng CL. mSphere. 2024 Oct 22:e0037124. doi: 10.1128/msphere.00371-24. Online ahead of print. PMID: 39436072
Chlamydia trachomatis Inc Ct226 is vital for FLI1 and LRRF1 recruitment to the chlamydial inclusion. Sturd NA, Knight LA, Wood MG, Durham L, Ouellette SP, Rucks EA. mSphere. 2024 Oct 15:e0047324. doi: 10.1128/msphere.00473-24. Online ahead of print. PMID: 39404459
Distinct impacts of each anti-anti-sigma factor ortholog of the chlamydial Rsb partner switching mechanism on development in Chlamydia trachomatis. Junker S, Singh V, Al-Saadi AGM, Wood NA, Hamilton-Brehm SD, Ouellette SP, Fisher DJ. Microbiol Spectr. 2024 Oct 29:e0184624. doi: 10.1128/spectrum.01846-24. Online ahead of print. PMID: 39470281
SS18-SSX Expression and Clinicopathologic Profiles in a Contemporary Cohort of Primary Paratesticular Synovial Sarcoma: A Series of Fourteen Patients. Lobo A, Mishra SK, Acosta AM, Kaushal S, Akgul M, Williamson SR, Sangoi AR, Aron M, Kandukuri SR, Shinde S, Sharma S, Jain E, Dhillon J, Deshwal A, Peddinti K, Jaiswal S, Das S, Kapoor R, Biswas G, Pradhan MR, Osunkoya AO, Pradhan D, Chakrabarti I, Jha S, Parwani AV, Shah RB, Amin MB, Cheng L, Mohanty SK. Am J Surg Pathol. 2024 Oct 25. doi: 10.1097/PAS.0000000000002323. Online ahead of print. PMID: 39449577
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors. Boby ML, Fearon D, Ferla M, Filep M, Koekemoer L, Robinson MC; COVID Moonshot Consortium‡; Chodera JD, Lee AA, London N, von Delft A, von Delft F, Achdout H, Aimon A, Alonzi DS, Arbon R, Aschenbrenner JC, Balcomb BH, Bar-David E, Barr H, Ben-Shmuel A, Bennett J, Bilenko VA, Borden B, Boulet P, Bowman GR, Brewitz L, Brun J, Bvnbs S, Calmiano M, Carbery A, Carney DW, Cattermole E, Chang E, Chernyshenko E, Clyde A, Coffland JE, Cohen G, Cole JC, Contini A, Cox L, Croll TI, Cvitkovic M, De Jonghe S, Dias A, Donckers K, Dotson DL, Douangamath A, Duberstein S, Dudgeon T, Dunnett LE, Eastman P, Erez N, Eyermann CJ, Fairhead M, Fate G, Fedorov O, Fernandes RS, Ferrins L, Foster R, Foster H, Fraisse L, Gabizon R, García-Sastre A, Gawriljuk VO, Gehrtz P, Gileadi C, Giroud C, Glass WG, Glen RC, Glinert I, Godoy AS, Gorichko M, Gorrie-Stone T, Griffen EJ, Haneef A, Hassell Hart S, Heer J, Henry M, Hill M, Horrell S, Huang QYJ, Huliak VD, Hurley MFD, Israely T, Jajack A, Jansen J, Jnoff E, Jochmans D, John T, Kaminow B, Kang L, Kantsadi AL, Kenny PW, Kiappes JL, Kinakh SO, Kovar B, Krojer T, La VNT, Laghnimi-Hahn S, Lefker BA, Levy H, Lithgo RM, Logvinenko IG, Lukacik P, Macdonald HB, MacLean … St. Patrick Reid See abstract for full author list ➔ Science. 2023 Nov 10;382(6671):eabo7201. doi: 10.1126/science.abo7201. Epub 2023 Nov 10. PMID: 37943932
Efficient trapping and destruction of SARS-CoV-2 using PECO-assisted Molekule air purifiers in the laboratory and real-world settings. Acharya A, Surbaugh K, Thurman M, Wickramaratne C, Myers P, Mittal R, Pandey K, Klug E, Stein SJ, Ravnholdt AR, Herrera VL, Rivera DN, Williams P, Santarpia JL, Kaushik A, Dhau JS, Byrareddy SN. Ecotoxicol Environ Saf. 2023 Oct 1;264:115487. doi: 10.1016/j.ecoenv.2023.115487. Epub 2023 Sep 18. PMID: 37729804
MUC16 Retention after Neoadjuvant Chemotherapy in Pancreatic Ductal Adenocarcinoma. Muilenburg KM, Ehrhorn EG, Olson MT, Isder CC, Klute KA, Talmon GA, Carlson MA, Ly QP, Mohs AM. Cancers (Basel). 2024 Oct 10;16(20):3439. doi: 10.3390/cancers16203439. PMID: 39456534
The spectrum of hematologic neoplasms in patients with Li-Fraumeni syndrome. Dimopoulos YP, Wang W, Wang SA, Loghavi S, DiNardo CD, Gerstein Y, Hu S, Tang Z, Ilagan CJL, Thakral B, El Hussein S, Xu J, Li S, Lin P, Patel KP, Ok CY, Medeiros LJ, Fang H. Am J Hematol. 2024 Oct 11. doi: 10.1002/ajh.27497. Online ahead of print. PMID: 39392132
Fatal meningoencephalitis associated with Ebola virus persistence in two survivors of Ebola virus disease in the Democratic Republic of the Congo: a case report study. Mukadi-Bamuleka D, Edidi-Atani F, Morales-Betoulle ME, Legand A, Nkuba-Ndaye A, Bulabula-Penge J, Mbala-Kingebeni P, Crozier I, Mambu-Mbika F, Whitmer S, Tshiani Mbaya O, Hensley LE, Kitenge-Omasumbu R, Davey R, Mulangu S, Fonjungo PN, Wiley MR, Klena JD, Peeters M, Delaporte E, van Griensven J, Ariën KK, Pratt C, Montgomery JM, Formenty P, Muyembe-Tamfum JJ, Ahuka-Mundeke S; EBOV Persistence Study Group. Lancet Microbe. 2024 Oct;5(10):100905. doi: 10.1016/S2666-5247(24)00137-X. Epub 2024 Sep 3. PMID: 39236738