COM research highlights, October 2023

Hanjun Wang, MD

The UNMC College of Medicine received grant and funding awards representing more than $3.9 million in new funding in August.

Hanjun Wang, MD, anesthesiology, received a grant of $628,228 from DHHS/NIH/NHLBI for a study of neural inflammation and exercise pressor reflex in heart failure.

Vijaya Bhatt, MBBS, internal medicine-oncology/hematology, received a grant of $610,706 from DHHS/NIH/NCI for a study on aging trajectories and outcomes of older adults with acute myeloid leukemia. Dr. Bhatt also received a grant of $25,749 from the University of British Columbia for the Applied Biomarkers in Late Effects (ABLE) study.

Mohan Krishnan, PhD, biochemistry/molecular biology, received a grant of $496,295 from the DHHS/NIH/NHLBI for a study of the liver-gut axis in neonatal anemia and its role in RBC transfusion associated gut injury.

Juhi Mishra, PhD, biochemistry/molecular biology, received a grant of $463,500 from the U.S. Army/USAMRAA/CDMRP for a study of stromal modulation by the secretory factors of neuroendocrine-like prostate cancer.

Yutong Liu, PhD, radiology, received a grant of $422,125 from DHHS/NIH/NIMH for a study of brain metabolic imaging biomarkers of HIV-1 infection during ART.

Surinder Batra, PhD, biochemistry/molecular biology, received a grant of $283,975 from the University of Pittsburgh for a study on the validation of biomarkers for early diagnosis and risk prediction of pancreatic neoplasms.

John Davis, PhD, obstetrics/gynecology, received a grant of $153,500 from DHHS/NIH/NICHD for a study on vascular remodeling in the ovary.

Jairam Krishnamurthy, MD, internal medicine-oncology/hematology, received a grant of $50,066 from Academic and Community Cancer Research United for a trial to evaluate immune-related biomarkers for pathological response in stage II-III HER2-positive breast cancer receiving neoadjuvant chemotherapy with subsequent randomization to multi-epitope HER2 vaccine vs. placebo in patients with residual disease post-neoadjuvant chemotherapy.

Trevor Van Schooneveld, MD, internal medicine-infectious diseases, received a grant of $49,958 from Johns Hopkins University for a diagnostic stewardship intervention to improve blood culture use among adult patients in acute care hospitals.

Cyrus Desouza, MBBS, internal medicine-DEM, received grants of $39,756 and $20,081 from the Nebraska Educational Biomedical Research Association to support efforts on the SURPASS study.

Eric Langewisch, MD, internal medicine-nephrology, received a grant of $35,635 from Cedars-Sinai Medical Center for an assessment of biomarker guided CNI substitution in kidney transplantation.

Ashley Wysong, MD, dermatology, received a grant of $23,898 from the American College for Mohs Surgery to providie patients with a personalized risk assessment for high-risk cutaneous squamous cell carcinoma: creation of a multicenter database and clinician use application for handheld devices.

Scott Campbell, PhD, pathology/microbiology, received a grant of $10,001 from the University of Colorado-Anschutz Medical Campus for the NC3 Tenant Project.

Industry-sponsored grants and contracts:

The following industry-sponsored grants and contracts were received.

Benjamin Teply, MD, internal medicine-oncology/hematology, received funding for a study of Disitamab Vedotin in combination with Pembrolizumab vs. chemotherapy in subjects with previously untreated locally advanced or metastatic urothelial carcinoma that expresses HER2.

Hani Haider, PhD, orthopaedic surgery, received funding for wear testing of the Enovis reverse shoulder replacement system.

Jairam Krishnamurthy, MD, internal medicine-oncology/hematology, received funding for a study to evaluate the efficacy and safety of HER2/neu Peptide GLSI 100 (GP2 + GM CSF).

Mark Rupp, MD, internal medicine-infectious diseases, received funding for an assessment of effect of ISDD on detection of central venous catheter colonization or contamination.

Daniel Murman, MD, neurological sciences, received funding for a study of the P38 alpha kinase inhibitor Neflamapimod in patients with dementia with Lewy bodies.

Greg Bociek, MD, internal medicine-oncology/hematology, received funding for a study of Zanubrutinib (BGB-3111) regimens in patients with B-cell malignancies.