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COM research highlights, December 2022

Iraklis Pipinos, MD, PhD

The UNMC College of Medicine received grant and funding awards representing nearly $6.7 million in new funding in October.

Iraklis Pipinos, MD, PhD, surgery-vascular surgery, received a grant of $631,128 from DHHS/NIH/NIA for a study on MitoQ treatment of claudication: myofiber and micro-vessel pathology.

Keshore Bidasee, PhD, pharmacology/experimental neuroscience, received a grant of $624,697 from DHHS/NIH/NHLBI to study diastolic heart failure in HIV-1 infection.

Surinder Batra, PhD, biochemistry and molecular biology, received a grant of $307,117 from the H. Lee Moffitt Cancer Center to study novel therapy to inhibit IPMN progression.

Steve Yeh, MD, ophthalmology and visual sciences, received a grant of $300,000 from the U.S. Agency for International Development for the West African Center of Excellence in Vision Care.

Santhi Gorantla, PhD, pharmacology/experimental neuroscience, received a grant of $230,250 from DHHS/NIH/NIMH for a study examining HIV-mediated disruption of CNS immune homeostasis.

Siddappa Byrareddy, PhD, pharmacology/experimental neuroscience, received a grant of $195,496 from the University of Minnesota for a study targeting CNS reservoirs with CAR/CXCR5 T cells for the long-term remission of HIV.

Javeed Iqbal, PhD, pathology/microbiology, received a grant of $151,865 from the University of Texas MD Anderson Cancer Center for a study of the role of heat shock protein 70 as a mediator and therapeutic target in T-cell lymphomas.

Joshua Santarpia, PhD, pathology/microbiology, received a grant of $147,001 from the National Strategic Research Institute for “Octopus.”

Jingwei Xie, PhD, surgery-transplant, received a grant of $117,727 from the University of Missouri-Columbia for a study of multifunctional porous soft materials for user-friendly skin-interfaced bimodal cardiac patches with long-term biocompatibility and antimicrobial property.

Howard Gendelman, MD, pharmacology/experimental neuroscience, received a grant of $114,820 from the University of California-Davis for the creation of a polygenic humanized mouse model for HIV-1.

Vijay Shivaswamy, MBBS, internal medicine-DEM, received six grants totaling $48,390 from the Nebraska Educational Biomedical Research Association as ICA.

Travis McCumber, PhD, genetics, cell biology and anatomy, received a grant of $6,000 from the University of Nebraska at Omaha’s NASA Nebraska Space Grant Fellowship.

Industry-sponsored grants and contracts:

The following industry-sponsored grants and contracts were received.

Howard Fox, MD, PhD, neurological sciences, received funding for the NTTC Data Coordinating Center.

Maegen Wallace, MD, orthopaedic surgery, received funding for a study to assess the efficacy and safety of setrusumab in subjects with osteogenesis imperfecta.

Diana Florescu, MD, internal medicine-infectious diseases, received funding for a study to evaluate the safety and tolerability, pharmacokinetics, and antiviral activity of maribavir for the treatment of cytomegalovirus (CMV) infection in children and adolescents.

Ronald Zolty, MD, PhD, internal medicine-cardiovascular, received funding for a study to evaluate the safety, tolerability, and pharmcokinetics of four weeks treatment with BAY 2413555.

Scott Campbell, PhD, pathology/microbiology, received funding for “FDA Synensys BAA PMWP 214; BAA No. FDABAA-22-00123.”

Alex Hewlett, DO, internal medicine-GI, received funding for a study to evaluate the long-tern safety of CC-93538.

Mridula Krishnan, MBBS, internal medicine-oncology/hematology, received funding for a study of atezolizumab and bevacizumab in Child-Pugh B7 hepatocellular carcinoma.

Samiksha Fouzdar Jain, MD, ophthalmology and visual sciences, received funding for a study to evaluate the safety of DEXYCU for the treatment of inflammation following ocular surgery for childhood cataract.

Benjamin Tepley, MD, internal medicine-oncology/hematology, received funding for a study of modern immunotherapy in BCG-relapsing urothelial carcinoma of the bladder.