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Research highlights

John Dickinson, MD, PhD

The UNMC College of Medicine received grant and funding awards representing $2,535,166 in new funding in April.

  • John Dickinson, MD, PhD, internal medicine-pulmonary, received a grant of $523,542 from DHHS/NIH/NHLBIU to study whether autophagy-mediated mucin degradation is necessary for resolution of mucous metaplasia.
  • Stacey Gilk, PhD, pathology/microbiology, received a grant of $184,510 from DHHS/NIHNI/AID to study intracellular IL-17 signaling during coxiella burnetii infection.
  • Kelly Stauch, PhD, neurological sciences, received a grant of $108,609 from the Michael J. Fox Foundation for a study determining PINK1 and PRKN enzyme activities in vivo.
  • Rebekah Dawson, PhD, cellular and integrative physiology, received a grant of $84,118 from the Regenerative Research Foundation for a study characterizing human RPE cell proliferation to advance endogenous regeneration.
  • Carol Toris, PhD, ophthalmology and visual sciences, received a grant of $83,869 from the University of Tennessee Health Science Center for a study of a novel extended release glaucoma therapy for once-daily dosing.
  • W. Scott Campbell, PhD, pathology and microbiology, received a grant of $42,240 from the Association of Public Health Laboratories for LRN-B and LRN-C software development for NPHL capacity.
  • Ted Mikuls, MD, internal medicine-rheumatology, received a grant of $23,290 from the University of Alabama-Birmingham to study the functional and integrative omics of recurrent gout flares.
  • Kaleb Michaud, MD, internal medicine-rheumatology, received a grant of $15,000 from the Rheumatology Research Foundation for a resident research preceptorship.
  • Sachit Patel, MD, internal medicine-hematology/oncology, received a grant of $14,987 from the National Marrow Donor Program for a work order: Clinical transplant-related long-term outcomes of alternative donor allogeneic transplantation.
  • Vijay Shivaswamy, MBBS, internal medicine-DEM, received a grant of $9,215 from the Nebraska Educational Biomedical Research Foundation for an ICA for Payton Hurlbut.
  • Cyrus Desouza, MBBS, internal medicine-DEM, received a grant of $6,133 from the Nebraska Educational Biomedical Research Foundation for an ICA for Payton Hurlbut.
  • Donald Coulter, MD, pediatrics, received a grant of $4,972 from the Children’s Hospital of Philadelphia for specimen baking supplements.

Industry-sponsored grants and contracts:

The following industry-sponsored contracts and foundation grants were received. Information on clinical trials enrolling patients at UNMC can be found here.

  • Ronald Zolty, MD, PhD, internal medicine-cardiovascular, received funding for a study to evaluate the efficacy and safety of oral inhalation of GB002 for the treatment of WHO group 1 pulmonary arterial hypertension.
  • Apar Ganti, MD, internal medicine-oncology/hematology, received funding for a study to evaluate the safety and efficacy of lenvatinib in combination with pembrolizumab.
  • Aviva Abosch, MD, PhD, neurosurgery, received funding for a pilot study of DBS electrode switching patterns for treatment of Parkinson’s disease.
  • James Harper, MD, pediatrics, received funding for a study of oral FT-4202, a pyruvate kinase activator, in patients with sickle cell disease.
  • Cyrus Desouza, MBBS, internal medicine-DEM, received funding for a trial comparing the effect and safety of once weekly insulin icodec and once daily insulin degludec, as well as to study Effectiveness and safety of once weekly insulin icodec used with DoseGuide.
  • Matthew Lunning, DO, internal medicine-oncology/hematology, received funding for a study to evaluate a wearable temperature monitoring device in subjects receiving CAR-T therapy.