Clinical Trial Spotlight: Breast cancer

Diane Ehlers, Ph.D., in the UNMC Department of Neurological Sciences, is seeking participants for her study, “Physical Activity’s Relationship with Cancer and Cognition (SPARCC)” (IRB#: 091-19-FB)

About the study:

We are testing an exercise program, delivered in Omaha area fitness centers, in women living with breast cancer. Participants will be randomized to an exercise group or a usual care group. All participants will be asked to complete two testing visits and a set of questionnaires before the study begins and again three months later. Participants will also be invited to complete a brain MRI at UNMC, but this is not required for participation in the study. The following provides more details:

The study is seeking females:

  • Post-menopausal at time of breast cancer diagnosis
  • First, primary diagnosis of Stage I-IIIa breast cancer
  • Completed primary treatment (i.e., surgery, chemotherapy, and/or radiation therapy).Women currently prescribed adjuvant endocrine therapy (e.g., aromatase inhibitor, estrogen receptor downregulator, selective estrogen receptor modulator) will be eligible to participate.
  • Available to attend exercise sessions three times weekly for 12 weeks
  • No scheduled travel for greater than seven consecutive days during the intervention
  • Agree to be randomized to an exercise group or usual care group
  • English reading and speaking
  • Receive physician’s clearance to participate in exercise
  • Provide written informed consent to participate in the study.

Participants are expected:

  • To attend two testing visits before the study and three months later, including:
    • Treadmill exercise test
    • Neurocognitive assessments including cognitive games and electroencephalography (EEG)
    • Questionnaires
    • Wear an activity monitor during daily life for seven days
  • Some individuals will be invited to complete a brain MRI at the Core for Advanced MRI (CAMRI) at UNMC; however, participation in this aspect of the study is not required.
  • Those in the exercise intervention group will be expected to attend 36 supervised exercise sessions with a fitness trainer three times per week for 12 weeks
    • Schedules are based on participant time and location preference and trainer availability

To express interest in participating, contact:

Lindsey Hanson at 402-559-6870, lindsey.hanson@unmc.edu or enl@unmc.edu.

The UNMC Department of Neurological Sciences’ “Current Studies” website

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