Yiannis Chatzizisis, MD, PhD, associate professor, Division of Cardiovascular Medicine, is co-PI for an awarded University of Nebraska Collaboration Initiative Seed Grant titled “Microscale Investigation of Mechanobiology of Atherosclerosis Using Novel Microfluidic Biochambers.” The grant is funded from 07/01/2017 through 06/30/2019.
According to the proposal abstract, “Our premise is that better understanding
of the implication of local biomechanical factors on the pathophysiology of
plaque rupture and erosion is critically important for the successful development of new diagnostic and therapeutic strategies.”
Also, according to the application, “The objective of this proposal is to couple state-of-the-art microscale flow measurements and simulation with equally novel cell co-culturing capabilities, to enable systematic
investigation of the mechanobiology of atherosclerosis.”