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UNMC Eye Researcher, Wallace Thoreson, Ph.D., Receives $180,000 Grant

University of Nebraska Medical Center eye researcher, Wallace Thoreson,

Ph.D., associate professor of ophthalmology and pharmacology, has received

a $180,000 Career Development Award from Research to Prevent Blindness.

The grant, provided over a four-year period, is awarded to attract university

scientists and physicians to eye research.

Research to Prevent Blindness is the world’s leading voluntary organization

in support of eye research. At 56 medical institutions nationwide, it supports

investigations into all blinding eye diseases.

Dr. Thoreson said he will use the award to do research and purchase

supplies and equipment. Im thrilled to have it. It will provide a nice

base to fund research, he said.

His research involves studying nerves in the eye and retina and how

mechanisms of sight communicate with the brain. He works with colleagues,

Iqbal Ahmad, Ph.D. and David Chacko, M.D., Ph.D., to study macular degeneration,

a leading cause of blindness in people over 75 years old.

The researchers have isolated cells in the retinas of embryonic rats

in what appears to be a major step in eventually allowing retinal transplants

to be performed in humans. The transplants could correct vision loss caused

by macular degeneration and retinitis pigmentosa, two of the most common

diseases causing blindness.

It is estimated that 10 million Americans suffer from macular degeneration.

It is more common in advanced ages, as nearly a quarter of people age 65

and older have some manifestations of the disease. With the Baby Boom Generation

in America growing older, the incidence of macular degeneration is expected

to increase dramatically.

Dr. Thoreson earned his bachelors degree in biology in 1981 from Carleton

College in Northfield, Minn., and received his doctoral degree in physiology

and neuroscience in 1989 from the University of Minnesota. He joined UNMC

in 1993 and was named assistant professor with appointments in the departments

of ophthalmology and pharmacology. In 1999, he was named associate professor

for both departments. Prior to joining UNMC, he worked nine years in various

research capacities at the University of Minnesota.

UNMC is the only public academic health science center in the state.

Through its commitment to research, education, outreach and patient care,

UNMC has established itself as one of the country’s leading centers for

cancer research and treatment and solid organ transplantation. Nearly $31

million in research grants and contracts were awarded to UNMC scientists

during the past fiscal year. In addition, UNMCs educational programs are

responsible for training more health professionals practicing in Nebraska

than any other institution.