Research Provides New Technology at UNMC/NHS to Detect Osteoporosis Risk Quickly, at Lower Cost

Osteoporosis, a chronic, disabling yet preventable health problem for

women, can now be monitored in a fast, safe, painless and cost-effective

way at the Olson Center for Womens Health, part of the University of Nebraska

Medical Center and Nebraska Health System. Since August, the center has

been providing screening services and education about osteoporosis and

how to prevent it.

Osteoporosis, known as the silent thief, progresses without symptoms

or pain until bones start to break, generally in the hip, spine or wrist.

“Osteoporosis can get so bad that just stepping off a curb or sneezing

can break bones, said Anne Miller-Bode, a nurse practitioner with the

center. It is a painful, immobilizing disease.

As many women will die of a hip fracture as will die from breast cancer,

according to the National Osteoporosis Foundation.


Researchers at the Olson Center for Womens Health were involved in

a national clinical trial for the Lunar Achilles+ Ultrasonometer. The ultrasonometer,

which measures heel bone thickness, is a new screening tool for identifying

and monitoring bone loss, said David Baldwin, Ph.D., coordinator of research

and development for the center.

Dr. Baldwin and Miller-Bode collaborated in the research with J.C. Gallagher,

M.D., Creighton University School of Medicine.


The thickness of the heel bone closely correlates to the measurement

we get from the hip, Dr. Baldwin said.

The two-foot-square, portable instrument was approved by the U.S. Food

and Drug Administration in June. The patients foot rests in a compartment

that fills with warm water while the ultrasound wave measures the bones

strength, flexibility and density. It is as reliable as the conventional

X-ray densitometry methods used to identify and monitor bone loss, Dr.

Baldwin said.

Were excited about this new instrument. This will help us easily screen

and identify patients who are at risk for osteoporosis, Dr. Baldwin said.

More than 28 million Americans, mostly women, are at high risk of developing

osteoporosis, yet, a Gallup survey of women ages 45 to 75 indicates that

three out of four women have never spoken to their doctor about the disease.

Caucasian and Asian women seem to have a greater risk of developing

osteoporosis. The risk factor for African-American women is about one-half

and for Hispanic-American women it is about one-third that of Caucasian

women.

The good news is osteoporosis can be prevented, said Miller-Bode.

If a woman at the age of 40 knows she is at risk for osteoporosis, then

she can alter her lifestyle now to prevent the disease. Its hard to rebuild

bone once its lost.

Bone mass loss is a significant health problem for women. After reaching

a peak at about age 25 to 35, bone mass declines with age, she said.

After women reach their peak in bone density, they begin to lose up

to 5 percent of bone mass every year before and after menopause. Bone mass

loss slows when a woman is in her 70s, but by the time she is 80, she could

lose 40 percent of her peak bone mass, Miller-Bode said.

Risk factors for osteoporosis include: inadequate calcium intake, physically

inactive, heavy caffeine intake, history of chronic disease such as diabetes

and hyperthyroidism, family history of osteoporosis or fractures, underweight,

pre- or post-menopausal, athletic amenorrhea, heavy smoker, consume at

least one drink of alcohol each day, and consuming drugs that are known

to decrease bone density.

In our clinic, we provide education and prevention counseling and screening.

If we can get women to peak their bone mass at a higher level, their chance

of developing osteoporosis will be reduced, Miller-Bode said.

Two common ways of preventing osteoporosis are diet and exercise. Yet,

excessive diet and exercise also can rob bones of calcium.

Athletes are at high risk because they have low body fat. Estrogen

is stored in fat cells. If there is too little or too much fat, the menstrual

cycle is affected. There isnt a proper balance of female hormones, she

said.

For that same reason, women who have eating disorders also are considered

high risk.

There are so many women who are at risk and are missed because they

dont get screened. This new method will have a tremendous impact on osteoporosis

prevention because its so user-friendly and costs less than the standard

X-ray absorptiometry (DEXA), Miller-Bode said.

She said ideally, as the Lunar Achilles+ Ultrasonometer becomes more

widely available, women could get the screening during their annual check-ups.

Some insurance companies pay for the screening or a portion of it.

Women who want to get a bone density test can be referred to the clinic

through their physician or call themselves. The test takes only 10 minutes

and can be performed during an office visit. Results are ready by the time

the patient puts her shoes on. Results will be discussed with the patient

and forwarded to the patients physician.

For more information, call the Olson Center for Womens Health at (402)

559-4212.

UNMC is the only public academic health science center in the state. 

Through its commitment to research, education and patient care, UNMC has

established itself as one of the country’s leading centers for cancer research

and treatment and solid organ transplantation.  More than $34 million

in research grants and contracts are awarded to UNMC scientists annually. 

In addition, UNMC’s educational programs are responsible for training more

health professionals practicing in Nebraska than any other institution.