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University of Nebraska Medical Center

Benita McVicker, PhD

Associate Professor, Division of Gastroenterology and Hepatology

402-995-3369

Benita McVicker, PhD
Research in Dr. McVicker’s lab involves the study of altered protein trafficking and hepatocellular injury in animal models of alcohol-associated liver disease; the role of alcohol in the potentiation of colorectal liver metastases; the study of hepatic stellate cell transformation and models of liver fibrosis; targeting profibrotic mechanisms using anti-miRNA nanoparticles; and pre-clinical assessments using human precision-cut liver slices.

Information

Research Interests
  • Altered protein trafficking and hepatocellular injury in animal models of alcohol-associated liver disease
  • The role of alcohol in the potentiation of colorectal liver metastases
  • The study of hepatic stellate cell transformation and models of liver fibrosis
  • Targeting profibrotic mechanisms using anti-miRNA nanoparticles
  • Pre-clinical assessments using human precision-cut liver slices

Publications

Active Grant Support

Active

  • "Development of delivery methods for combination microRNA treatment of alcohol-associated liver disease" Co-Investigator (Oupicky), DHHS/NIH/NIAAA
  • "Nebraska Center of Nanomedicine (Phase III)" Other (Oupicky), DHHS/NIH/NIGMS
  • "IPA - Zuzana Sulcova" Principal Investigator, VA Medical Center - Omaha

Pending

  • "Alcohol Center Of Research-Nebraska (ACORN)" Other (Casey), DHHS/NIH/NIAAA
Education
  • BS: Chemistry, College of St. Mary, Omaha, Nebraska, 1987
  • PhD: Biochemistry, University of Nebraska Medical Center, 1997
  • Postdoctoral Training: Research Scientist, University of Nebraska Medical Center