Category: Science and Tech
What are the differences in transmissibility between novel and emerging SARS-CoV-2 variants?
Medical News – Currently, the majority of reporting of secondary attack rates (SAR) in coronavirus disease 2019 (COVID-19) have defined secondary infection as recent polymerase chain reaction (PCR) positivity in a contact who is displaying symptoms. By only including those who are symptomatic while having detectable viral ribonucleic acid (RNA) during sampling, this method undercounts […]
Sep 30, 2022
Repurposing existing drugs to fight new COVID-19 variants
Michigan State University – MSU researchers are using big data and AI to identify current drugs that could be applied to treat new COVID-19 variants. Finding new ways to treat the novel coronavirus and its ever-changing variants has been a challenge for researchers, especially when the traditional drug development and discovery process can take years. […]
Sep 29, 2022
Zoonotic diseases like COVID-19 and monkeypox will become more common, experts say
NPR – Cases of monkeypox are on the rise in the U.S., with about 67,600 global cases, including about 25,500 in the U.S. Simultaneously, the world is still facing a COVID-19 pandemic, despite the number of cases tapering off. Researchers say these types of viruses, known as zoonotic diseases, or ones that spread between humans and animals, will […]
Sep 29, 2022
Remdesivir resistance in transplant recipients with persistent COVID-19
Clinical Infectious Diseases – New mutations conferring resistance to SARS-CoV-2 therapeutics have important clinical implications. We describe the first cases of an independently acquired V792I RNA-dependent RNA polymerase mutation developing in renal transplant recipients after remdesivir exposure. Our work underscores the need for augmented efforts to identify concerning mutations and address their clinical implications. Download […]
Sep 28, 2022
SARS-CoV-2 mutation leads to resistance to remdesivir in 2 patients
CIDRAP – A report published yesterday in Clinical Infectious Diseases describes a new SARS-CoV-2 mutation that confers resistance to the COVID-19 antiviral drug remdesivir in two persistently infected kidney transplant recipients treated with immunosuppressive drugs. NYU researchers identified the V792I RNA-dependent 25 RNA polymerase mutation in the transplant patients, who were hospitalized and experienced life-threatening COVID-19 complications […]
Sep 28, 2022
These scientists traced a new coronavirus lineage to one office — through sewage
Nature – Virologist Dave O’Connor admits that he was getting desperate when he started asking dog owners for poo samples. For much of 2022, O’Connor, at the University of Wisconsin–Madison, and his colleagues have been tracking a heavily mutated variant of SARS-CoV-2, the virus that causes COVID-19. Early this year, they discovered the variant in […]
Sep 26, 2022
Viruses May Be “Watching” You – Lying in Wait Before Multiplying and Killing
SciTechDaily – Viruses may be ‘watching’ you – some microbes lie in wait until their hosts unintentionally give them the signal to start multiplying and kill them. Especially after more than two years of the COVID-19 pandemic, many people picture a virus as a nasty spiked ball – essentially a mindless killer that gets into a cell […]
Sep 26, 2022
How COVID-19 stole our sense of smell
Chemical Engineering News – SARS-CoV-2 has left thousands with a distorted or lost sense of smell. This population is helping researchers identify what happens when smell goes wrong and what might help. Researchers are getting a clearer idea of how. This understanding and a growing awareness of olfactory disorders could help others facing smell loss […]
Sep 26, 2022
New COVID variants may evade current treatments—or render them entirely ineffective, experts say
Fortune – Future COVID variants are expected to be more transmissible and perhaps better at evading the immune system. And they might even render treatments for patients like monoclonal antibodies “less effective,” the World Health Organization’s pandemic lead said Thursday. Van Kerkhove said that the WHO is keeping an eye on Omicron variants BA.5—currently dominant […]
Sep 23, 2022
An ACE2-dependent Sarbecovirus in Russian bats is resistant to SARS-CoV-2 vaccines
PLoS Pathogens – Spillover of sarbecoviruses from animals to humans has resulted in outbreaks of severe acute respiratory syndrome SARS-CoVs and the ongoing COVID-19 pandemic. Efforts to identify the origins of SARS-CoV-1 and -2 has resulted in the discovery of numerous animal sarbecoviruses–the majority of which are only distantly related to known human pathogens and […]
Sep 23, 2022