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University of Nebraska Medical Center

Category: Published Research

Emergence and spread of two SARS-CoV-2 variants of interest in Nigeria

Identifying the dissemination patterns and impacts of a virus of economic or health importance during a pandemic is crucial, as it informs the public on policies for containment in order to reduce the spread of the virus. In this study, we integrated genomic and travel data to investigate the emergence and spread of the SARS-CoV-2 […]

Feb 13, 2023

Highly pathogenic avian influenza A(H5N1) virus infection in farmed minks, Spain, October 2022

(Eurosurveillance) This report describes an outbreak of highly pathogenic avian influenza (HPAI) A(H5N1) detected in intensively farmed minks in Europe, which occurred in the Galicia region in northwest Spain in October 2022. We present an in-depth description of the epidemiological, clinical and genetic investigations of this outbreak affecting a single farm and discuss public health […]

Feb 8, 2023

Phenotypic effects of mutations observed in the neuraminidase of human origin H5N1 influenza A viruses

(PLoS Pathogens) Global spread and regional endemicity of H5Nx Goose/Guangdong avian influenza viruses (AIV) pose a continuous threat for poultry production and zoonotic, potentially pre-pandemic, transmission to humans. Little is known about the role of mutations in the viral neuraminidase (NA) that accompanied bird-to-human transmission to support AIV infection of mammals. Here, after detailed analysis […]

Feb 8, 2023

First molecular detection of SARS-CoV-2 virus in cockroaches

Biologia Coronavirus is one of the main pathogens that primarily targets the human respiratory system. There are several ways to transmit this virus, such as direct contact or droplets spread by coughing or sneezing, and direct contact with fomites and surfaces is another way. This cross-sectional study was conducted in Shiraz, southern Iran, in 2021. […]

Feb 7, 2023

Highly pathogenic avian influenza A(H5N1) virus infection in farmed minks, Spain, October 2022

(Eurosurveillance) This report describes an outbreak of highly pathogenic avian influenza (HPAI) A(H5N1) detected in intensively farmed minks in Europe, which occurred in the Galicia region in northwest Spain in October 2022. We present an in-depth description of the epidemiological, clinical and genetic investigations of this outbreak affecting a single farm and discuss public health […]

Jan 31, 2023

Plasma from patients with pulmonary embolism show aggregates that reduce after anticoagulation

(Nature) Background Microclots, a term also used for amyloid fibrin(ogen) particles and henceforth named aggregates, have recently been reported in the plasma of patients with COVID-19 and long COVID. These aggregates have been implicated in the thrombotic complications of these diseases. Methods Plasma samples from 35 patients with acute pulmonary embolism were collected and analysed […]

Jan 31, 2023

Planning for Mpox on a College Campus: A Model-Based Decision-Support Tool

(Annals of Internal Medicine) In spring and summer 2022, an outbreak of mpox occurred worldwide, largely confined to men who have sex with men (MSM). There was concern that mpox could break swiftly into congregate settings and populations with high levels of regular frequent physical contact, like university campus communities. Objective: To estimate the likelihood […]

Jan 31, 2023

A systematic review and meta-analysis of the evidence on learning during the COVID-19 pandemic

(Nature) To what extent has the learning progress of school-aged children slowed down during the COVID-19 pandemic? A growing number of studies address this question, but findings vary depending on context. Here we conduct a pre-registered systematic review, quality appraisal and meta-analysis of 42 studies across 15 countries to assess the magnitude of learning deficits […]

Jan 31, 2023

Assessment of COVID-19 as the Underlying Cause of Death Among Children and Young People Aged 0 to 19 Years in the US

(JAMA) Question  Where does COVID-19 rank as an underlying cause of death for children and young people aged 0 to 19 years in the US? Findings  Among children and young people aged 0 to 19 years in the US, COVID-19 ranked eighth among all causes of deaths, fifth in disease-related causes of deaths (excluding unintentional injuries, assault, […]

Jan 31, 2023

Assessment of Efficacy and Safety of mRNA COVID-19 Vaccines in Children Aged 5 to 11 Years

(JAMA Pediatrics)   Are messenger RNA (mRNA) COVID-19 vaccines safe and effective in children aged 5 to 11 years? In this systematic review and meta-analysis including 17 studies with 10 935 541 vaccinated and 2 635 251 unvaccinated children aged 5 to 11 years, COVID-19 vaccination was associated with lower risks of SARS-CoV-2 infection, symptomatic COVID-19, hospitalization, and multisystem inflammatory […]

Jan 24, 2023