Category: Published Research
Greater traditionalism predicts COVID-19 precautionary behaviors across 27 societies
Nature People vary both in their embrace of their society’s traditions, and in their perception of hazards as salient and necessitating a response. Over evolutionary time, traditions have offered avenues for addressing hazards, plausibly resulting in linkages between orientations toward tradition and orientations toward danger. Emerging research documents connections between traditionalism and threat responsivity, including […]
Apr 11, 2023
Nature COVID-19 is a newly recognized illness with a predominantly respiratory presentation. Although initial analyses have identified groups of candidate gene biomarkers for the diagnosis of COVID-19, they have yet to identify clinically applicable biomarkers, so we need disease-specific diagnostic biomarkers in biofluid and differential diagnosis in comparison with other infectious diseases. This can further […]
Apr 6, 2023
Covid-19 Surveillance Testing and Resident Outcomes in Nursing Homes
NEJM Despite widespread adoption of surveillance testing for coronavirus disease 2019 (Covid-19) among staff members in skilled nursing facilities, evidence is limited regarding its relationship with outcomes among facility residents. METHODS Using data obtained from 2020 to 2022, we performed a retrospective cohort study of testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among […]
Apr 4, 2023
Frontiers in Immunology Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic disease considered to be triggered by viral infections in a majority of cases. Symptoms overlap largely with those of post-acute sequelae of COVID-19/long-COVID implying common pathogenetic mechanisms. SARS-CoV-2 infection is risk factor for sustained latent virus reactivation that may account for the symptoms of […]
Apr 4, 2023
Surveillance of SARS-CoV-2 in the environment and animal samples of the Huanan Seafood Market
Preprint AbstractEmerging in December 2019, coronavirus disease 2019 (COVID-19) eventually became a pandemic and has posed a tremendous threat to global public health. However, the origins of SARS-CoV-2, the causative agent of COVID-19, remain to be determined. It has reported that a certain number of the early case clusters had a contact history with Huanan […]
Mar 22, 2023
(Cambridge Press) In a large healthcare worker cohort, we quantified the association between behaviors and risk of coronavirus disease 2019 (COVID-19) during different pandemic phases, adjusting for prior infection and vaccination. Individual characteristics, including personal concerns, were associated with these behaviors. Public health messaging should target high-risk populations and behaviors as the pandemic evolves. Transmission […]
Mar 14, 2023
JAMA Question Do postacute sequelae of SARS-CoV-2 increase risks of 1-year adverse outcomes? Findings In this case-control study of 13 435 US adults with post–COVID-19 condition (PCC) and 26 870 matched adults without COVID-19, the adults with PCC experienced increased risks for a number of cardiovascular outcomes, such as ischemic stroke. During the 12-month follow-up period, 2.8% of the […]
Mar 7, 2023
Longitudinal Assessment of Chest CT Findings and Pulmonary Function in Patients after COVID-19
(Radiology) Information on pulmonary sequelae and pulmonary function at 2 years post recovery from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are lacking.
Feb 21, 2023
(PLoS Biology) Although ACE2 is the primary receptor for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, a systematic assessment of host factors that regulate binding to SARS-CoV-2 spike protein has not been described. Here, we use whole-genome CRISPR activation to identify host factors controlling cellular interactions with SARS-CoV-2. Our top hit was a TLR-related cell […]
Feb 17, 2023
Lancet Preprint Background: Previous studies have found a correlation between coronavirus disease 2019 (COVID-19) and changes in brain structure and cognitive impairment, but it remains unclear whether COVID-19 causes structural changes to the brain and which specific brain regions may be affected. Herein, we conduct a Mendelian randomization (MR) study to determine this causal relationship […]
Feb 16, 2023