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University of Nebraska Medical Center

Category: Emerging Infectious Diseases

Merck to donate Ebola vaccine candidate for research program in Uganda

(Reuters) Merck said on Tuesday it was planning to produce and donate investigational Sudan ebolavirus vaccine to a global non-profit organization’s research program in Uganda, which is facing an outbreak of the disease. The investigational vaccine that will be donated to IAVI is similar to Merck’s Ervebo vaccine, which is approved against the Zaire ebolavirus […]

Oct 25, 2022

Anti-Inflammatory Agents May Have Role in COVID-19 Pneumonia

(MedPageToday) Infliximab and abatacept showed trends for improved outcomes in ACTIV-1 IM trial. Use of the anti-inflammatory agents infliximab (Remicade) and abatacept (Orencia) added to standard of care showed a hint of improvement in outcomes for patients hospitalized with COVID-19 pneumonia, according to results from the ACTIV-1 IM trial. Compared with a median time to […]

Oct 25, 2022

During the first year of the pandemic, men died from COVID at a much higher rate than women

(CDC) Death rates in the United States are higher in rural than urban areas, andthe difference has grown over the last 2 decades (1). Death rates for all ofthe 10 leading causes of death in 2019 were higher in rural than urban areas(1). In 2020, deaths due to COVID-19 became the third leading cause ofdeath […]

Oct 25, 2022

Got questions about the timing of flu and Covid vaccines? Here’s what experts say

(STAT) Over the past few weeks, cases of flu have begun to creep up across the U.S., with spikes in the southeast and south central part of the country. Flu hospitalizations are also on the rise. According to the Centers for Disease Control and Prevention’s influenza tracking team, all signs point to an earlier than usual […]

Oct 25, 2022

Omicron keeps finding new evolutionary tricks to outsmart our immunity

(NPR) Throughout the pandemic, the virus that causes COVID-19 has been evolving fast, blindsiding the world with one variant after another. But the World Health Organization hasn’t given a SARS-CoV-2 variant a Greek name in almost a year, a move that’s reserved for new variants that do or could have significant public health impacts, such […]

Oct 25, 2022

We May Have Only a Few Months to Prevent the Next Pandemic

(NYT) Dr. Spencer is an emergency doctor and professor at Brown. He survived Ebola in 2014 after treating patients in Guinea and recently treated Covid-19 patients in New York City. I’m often asked what it felt like to have Ebola. Eight years later, I still struggle to respond. But the truth is that having Ebola […]

Oct 25, 2022

A booster is your best shot now

(Ground Truths Blog) I know it’s hard to keep track of the new variants, with esoteric designations and without names (Hello WHO, where are you?). But several of these are quite troubling because their growth advantage compared to BA.5 (the wave we’re getting over) is substantial, chiefly related to their ability to work around our […]

Oct 24, 2022

Long-COVID post-viral chronic fatigue and affective symptoms are associated with oxidative damage, lowered antioxidant defenses and inflammation: a proof of concept and mechanism study

(Nature) The immune-inflammatory response during the acute phase of COVID-19, as assessed using peak body temperature (PBT) and peripheral oxygen saturation (SpO2), predicts the severity of chronic fatigue, depression and anxiety symptoms 3–4 months later.

Oct 24, 2022

Modeling the spatio‑temporal spread of COVID‑19 cases, recoveries and deaths and effects of partial and full vaccination coverage in Canada

(Nature) The purposes of our study are to map high-risk areas in Canada as well as quantifying the effects of vaccination intervention and socio-demographic factors on the transmission rates of infection, recovery, and death related to COVID-19. The data of this research included weekly number of COVID‑19 cases, recovered, and dead individuals from 2020 through […]

Oct 24, 2022

Children’s hospitals grapple with a nationwide surge in RSV infections

(NPR) An unseasonably early spike in respiratory syncytial virus cases among young children is pushing some hospitals to capacity. RSV, as it’s called, is a respiratory virus that mostly manifests as a mild illness with cold-like symptoms in adults but can cause pneumonia and bronchiolitis in very young children. It can be life-threatening in infants and young […]

Oct 24, 2022

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