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University of Nebraska Medical Center

Category: Emerging Infectious Diseases

Increased household transmission and immune escape of the SARS-CoV-2 Omicron compared to Delta variants

Nature – Understanding the epidemic growth of the novel SARS-CoV-2 Omicron variant is critical for public health. We compared the ten-day secondary attack rate (SAR) of the Omicron and Delta variants in households using Norwegian contact tracing data, December 2021 – January 2022. Omicron SAR was higher than Delta, with a relative risk (RR) of […]

Sep 29, 2022

Chronic neuropsychiatric sequelae of SARS-CoV-2: Protocol and methods from the Alzheimer’s Association Global Consortium

Translational Research and Clinical Interventions – Coronavirus disease 2019 (COVID-19) has caused >3.5 million deaths worldwide and affected >160 million people. At least twice as many have been infected but remained asymptomatic or minimally symptomatic. COVID-19 includes central nervous system manifestations mediated by inflammation and cerebrovascular, anoxic, and/or viral neurotoxicity mechanisms. More than one third […]

Sep 29, 2022

Study aims to understand how SARS-CoV-2 affects the brain long-term

Medical News – In addition to the lungs, COVID-19 also affects the central nervous system (CNS) through anoxic, viral neurotoxicity, inflammation, and cerebrovascular mechanisms. As a result, about one-third of COVID-19 patients develop different neurologic problems, such as seizures, loss of sense of smell or taste, and stroke. Related study in Translational Research and Clinical Interventions

Sep 29, 2022

Effectiveness of primary series and booster vaccination against SARS-CoV-2 infection and hospitalisation among adolescents aged 12–17 years in Singapore: a national cohort study

The Lancet – Singapore offered the BNT162b2 vaccine (tozinameran; Pfizer-BioNTech) to adolescents aged 12–17 years in May 18, 2021, and extended booster vaccines to this group in Jan 21, 2022. Literature on the effectiveness of primary series and booster vaccination among adolescents is scarce outside of Europe and North America. We aimed to determine primary […]

Sep 29, 2022

What comes after Omicron? New variants are emerging.

National Geographic – Infections over the last three months have been dominated by new sublineages of Omicron: BA.2, BA.2.12.1, BA.4., and BA.5. In the U.K., symptomatic infections have steadily increased since August 27—the day they hit lowest level this year—according to the ZOE COVID-19 study, an App-based project in which patients enter their symptoms on their […]

Sep 29, 2022

Mental Health During the COVID-19 Pandemic

NIH – Both SARS-CoV-2 and the COVID-19 pandemic have significantly affected the mental health of adults and children. In a 2021 study, nearly half of Americans surveyed reported recent symptoms of an anxiety or depressive disorder, and 10% of respondents felt their mental health needs were not being met. Rates of anxiety, depression, and substance […]

Sep 29, 2022

Uganda is racing to contain a deadly Ebola outbreak

CBS News – Ugandan Ministry of Health Officials said Tuesday that a total of 36 cases, including 18 confirmed and 18 more listed as probable, had been reported. There were 23 deaths within that number, five among confirmed cases and 18 among probable ones. Officials have confirmed to CBS News separately that five people are confirmed to […]

Sep 29, 2022

Ebola experimental vaccine trial may begin soon in Uganda

STAT News – A clinical trial of one or perhaps two experimental vaccines designed to protect against the Ebola Sudan virus could soon begin in Uganda, as long as the country agrees to allow the research to take place, an official of the World Health Organization said Wednesday. The trial could get underway within a couple […]

Sep 29, 2022

Repurposing existing drugs to fight new COVID-19 variants

Michigan State University – MSU researchers are using big data and AI to identify current drugs that could be applied to treat new COVID-19 variants. Finding new ways to treat the novel coronavirus and its ever-changing variants has been a challenge for researchers, especially when the traditional drug development and discovery process can take years. […]

Sep 29, 2022

Should I still be worried about monkeypox?

Washington Post – New monkeypox cases are declining in the United States, a trend public health officials and clinicians attribute to vaccination and changes in behavior. Eligible individuals who did not receive the monkeypox vaccine were about 14 times more likely to become infected than those who received a first dose of the two-dose vaccine, […]

Sep 29, 2022