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University of Nebraska Medical Center

Category: Monkeypox

UNMC tapped for trial of monkeypox treatment

(Nebraska Examiner) The University of Nebraska Medical Center is among more than 60 sites nationally that has been tapped for a trial study of a monkeypox treatment. The STOMP (Study of Tecovirimat for Human Monkeypox Virus) is a phase 3 trial evaluating the safety and effectiveness of the antiviral tecovirimat drug.

Nov 1, 2022

HIV Coinfection in Over 80% of Hospitalized Monkeypox Cases

(MedPageToday) In a cohort of patients hospitalized for monkeypox, four out of five had HIV and one in five died, CDC researchers said. Of the 57 adults hospitalized due to serious complications from monkeypox, 82.5% had HIV and 8.5% were receiving antiretroviral therapy, reported Maureen Miller, MD, of the CDC’s Monkeypox Emergency Response Team, and […]

Oct 28, 2022

Six people who tested positive for monkeypox have died, health departments confirm

(CNN) Six people who tested positive for monkeypox – two in New York City, two in Chicago, one in Nevada and one in Maryland – have died, local health departments have confirmed. The New York City Department of Health and Mental Hygiene said it was “deeply saddened by the two reported deaths, and our hearts […]

Oct 24, 2022

Monkeypox after Occupational Needlestick Injury from Pustule

CDC EID – We report a case of monkeypox in a physician after an occupational needlestick injury from a pustule. This case highlights risk for occupational transmission and manifestations of the disease after percutaneous transmission: a short incubation period, followed by a solitary lesion at the injured site and later by systemic symptoms.

Oct 18, 2022

Monkeypox Virus Infection Resulting from an Occupational Needlestick — Florida, 2022

CDC – In August 2022, the Florida Department of Health notified CDC of a nurse who acquired monkeypox through an occupational exposure while providing care to a patient with monkeypox. To date, occupationally acquired Monkeypox virus (MPXV) infections in health care personnel (HCP) have been rarely reported during the 2022 multinational outbreak (1,2). This report describes the […]

Oct 18, 2022

Monkeypox treatment trial begins in the Democratic Republic of the Congo

NIH – A clinical trial to evaluate the antiviral drug tecovirimat, also known as TPOXX, in adults and children with monkeypox has begun in the Democratic Republic of the Congo (DRC). The trial will evaluate the drug’s safety and its ability to mitigate monkeypox symptoms and prevent serious outcomes, including death. The National Institute of Allergy and […]

Oct 12, 2022

FDA Clears Use of Monkeypox Testing Equipment

FDA – FDA issued an Emergency Use Authorization (EUA) to Abbott Molecular, Inc., for the Alinity m MPXV, a real-time polymerase chain reaction (PCR) test intended to detect monkeypox DNA using lesion swab specimens from individuals suspected of monkeypox virus infection. The Alinity m MPXV test is the first commercial test kit to be authorized for detection […]

Oct 10, 2022

Breakthrough Monkeypox Cases Seen Weeks After Second Jynneos Dose

MedPageToday – Most cases of monkeypox post-vaccination occurred within 2 weeks of the first Jynneos dose, a single-center study found, but some breakthrough cases developed weeks after a second dose of the vaccine. Of 90 individuals who tested positive for monkeypox after a single dose of Jynneos at a large monkeypox testing and vaccination site, […]

Oct 6, 2022

The monkeypox virus is mutating. Are scientists worried?

Nature – In some samples, large chunks of the virus’s genome have disappeared — but understanding whether the mutations affect its behaviour will be difficult. As researchers at the Minnesota Department of Health in St. Paul were sequencing samples of the monkeypox virus a few months ago, they made a surprising discovery. In one sample […]

Oct 5, 2022

CDC warns of severe illnesses from monkeypox as Ohio reports death of a monkeypox patient

CNN – The US Centers for Disease Control and Prevention issued a new warning to health care providers Thursday about severe illnesses in people with monkeypox. The alert comes as Ohio reported that an individual with monkeypox has died – the third known death of a patient with monkeypox in the United States. Ohio listed […]

Sep 30, 2022