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University of Nebraska Medical Center

Category: Marburg Virus

Cameroon – Anticipatory action for Marburg

Relief Web Since February 7, 2023, several suspected cases with symptoms of Marburg Hemorrhagic Fever have been declared in Equatorial Guinea in districts of Kie-Ntem province. On February 13, 2023, the first Marburg epidemic was declared by confirmation of a positive sample. Several contact cases are to be traced and Cameroon has recorded suspect cases […]

Mar 7, 2023

What is Marburg virus and should we be worried?

(The Conversation) An epidemic outbreak of Marburg virus in Equatorial Guinea, Central Africa, was confirmed this week, the first time the virus has occurred there. At least 16 cases have been detected, and nine deaths. There are no approved treatments for Marburg virus, which is closely related to Ebola virus, but vaccines are in development. Following an unprecedented […]

Feb 17, 2023

Marburg virus outbreak: researchers race to test vaccines

(Nature) Control measures such as quarantine could end the outbreak in Equatorial Guinea quickly — good news for inhabitants but a mixed blessing for clinical trials. Health officials worldwide are sprinting to test whether experimental vaccines can protect against a deadly illness, after Equatorial Guinea confirmed its first outbreak of Marburg virus disease on 13 […]

Feb 15, 2023

Cameroon detects two suspected cases of Marburg virus near Eq. Guinea

(Reuters) – Cameroonian authorities detected two suspected cases of Marburg disease on Monday in Olamze, a commune on the border with Equatorial Guinea, the public health delegate for the region, Robert Mathurin Bidjang, said on Tuesday. Equatorial Guinea officially declared its first outbreak of the Marburg virus, an illness similar to Ebola, on Monday. Neighbouring Cameroon had restricted movement along the […]

Feb 14, 2023

Safety, tolerability, and immunogenicity of the chimpanzee adenovirus type 3-vectored Marburg virus (cAd3-Marburg) vaccine in healthy adults in the USA: a first-in-human, phase 1, open-label, dose-escalation trial

(The Lancet) WHO has identified Marburg virus as an emerging virus requiring urgent vaccine research and development, particularly due to its recent emergence in Ghana. We report results from a first-in-human clinical trial evaluating a replication-deficient recombinant chimpanzee adenovirus type 3 (cAd3)-vectored vaccine encoding a wild-type Marburg virus Angola glycoprotein (cAd3-Marburg) in healthy adults.

Feb 14, 2023

Marburg vaccine shows promising results in first-in-human study

(NIH) A newly published paper in The Lancet shows that an experimental vaccine against Marburg virus (MARV) was safe and induced an immune response in a small, first-in-human clinical trial. The vaccine, developed by researchers at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, could someday be an important tool […]

Feb 14, 2023

Interministerial meeting coordinated by MINSABS after the health alert for Marburg hemorrhagic fever issued yesterday.

EQ Ministry of Health (Machine translated to English) Today, the Minister of Health and Social Welfare, accompanied by the presidential advisers on health, and WHO consultants based in the country, held an important meeting with the departments linked to the inter-ministerial management of the current epidemic of Marburg virus hemorrhagic fever. The Minister of State […]

Feb 14, 2023

What to know about the deadly Marburg virus as new outbreak emerges

(Washington Post) The deadly Marburg virus has surfaced this week for the first time in Equatorial Guinea, causing at least nine deaths in the west African nation, according to the World Health Organization. A handful of Marburg cases were identified in Ghana late last year. Although it remains “a very rare disease in people,” according to the Centers for Disease Control […]

Feb 14, 2023

EG MoH Statement

UPDATE STATEMENT SANITARY ALERT OF THE DAYFEBRUARY 8, 2023(Machine translated) The Government of the Republic of Equatorial Guinea, through the Ministry of Health and Social Welfare, issues the following update on the situation of the health alert of last February 8, communicated as a result of the unusual epidemiological situation detected in the districts of […]

Feb 13, 2023