Category: COVID
U.S. government to test Pfizer’s Paxlovid for long COVID
(Reuters) The U.S. National Institutes of Health’s $1 billion RECOVER Initiative has picked Pfizer Inc’s (PFE.N) antiviral drug Paxlovid as the first treatment it will study in patients with long COVID, organizers of the study said on Thursday. The complex medical condition involves more than 200 symptoms ranging from exhaustion and cognitive impairment to pain, fever and […]
Oct 28, 2022
Recurrence of Symptoms Following a 2-Day Symptom Free Period in Patients With COVID-19
(JAMA) Recurrence of symptoms after finishing treatment for COVID-19 with nirmatrelvir-ritonavir (Paxlovid) has become increasingly recognized.1–3 The biological underpinning of this phenomenon is unclear, and its etiology may be multifactorial, including rapid clearance of nirmatrelvir coupled with delayed immune responses or possible development of drug resistance.1–3 The contribution of treatment to symptom rebound needs to be differentiated […]
Oct 28, 2022
It’s a Bad Time to Be a Booster Slacker
(The Atlantic) And just like that, with the passing of Labor Day, fall was upon us. Seemingly overnight, six-packs of pumpkin beer materialized on grocery shelves, hordes of city dwellers descended upon apple orchards—and America rolled out new COVID boosters. The timing wasn’t a coincidence. Since the beginning of the pandemic, cases in North America […]
Oct 27, 2022
Neurologic, neurocognitive symptoms of COVID-19 persist for 1 year after diagnosis
(Healio Neurology) Persistent neurocognitive impairment, depression and anxiety were frequently reported in individuals with mild COVID-19 infection in Lima, Peru, according to a poster at ANA 2022. “Given the fact that this population has a different background, different culture and socioeconomic status, the outcomes aren’t necessarily going to be the same as those from high-income […]
Oct 27, 2022
Cardiovascular disease and mortality sequelae of COVID-19 in the UK Biobank
(BMJ) Objective To examine association of COVID-19 with incident cardiovascular events in 17 871 UK Biobank cases between March 2020 and 2021. Methods COVID-19 cases were defined using health record linkage. Each case was propensity score-matched to two uninfected controls on age, sex, deprivation, body mass index, ethnicity, diabetes, prevalent ischaemic heart disease (IHD), smoking, hypertension and high […]
Oct 25, 2022
People who caught mild Covid had increased risk of blood clots, British study finds
(NBC) Patients with mild Covid, defined as those not hospitalized, were 2.7 times more likely to develop blood clots, according to the study published in the British Medical Journal on Monday. Patients hospitalized with Covid were 27 times more likely to develop blood clots, 21 times more likely to suffer heart failure and 17 times […]
Oct 25, 2022
Anti-Inflammatory Agents May Have Role in COVID-19 Pneumonia
(MedPageToday) Infliximab and abatacept showed trends for improved outcomes in ACTIV-1 IM trial. Use of the anti-inflammatory agents infliximab (Remicade) and abatacept (Orencia) added to standard of care showed a hint of improvement in outcomes for patients hospitalized with COVID-19 pneumonia, according to results from the ACTIV-1 IM trial. Compared with a median time to […]
Oct 25, 2022
During the first year of the pandemic, men died from COVID at a much higher rate than women
(CDC) Death rates in the United States are higher in rural than urban areas, andthe difference has grown over the last 2 decades (1). Death rates for all ofthe 10 leading causes of death in 2019 were higher in rural than urban areas(1). In 2020, deaths due to COVID-19 became the third leading cause ofdeath […]
Oct 25, 2022
Got questions about the timing of flu and Covid vaccines? Here’s what experts say
(STAT) Over the past few weeks, cases of flu have begun to creep up across the U.S., with spikes in the southeast and south central part of the country. Flu hospitalizations are also on the rise. According to the Centers for Disease Control and Prevention’s influenza tracking team, all signs point to an earlier than usual […]
Oct 25, 2022
Omicron keeps finding new evolutionary tricks to outsmart our immunity
(NPR) Throughout the pandemic, the virus that causes COVID-19 has been evolving fast, blindsiding the world with one variant after another. But the World Health Organization hasn’t given a SARS-CoV-2 variant a Greek name in almost a year, a move that’s reserved for new variants that do or could have significant public health impacts, such […]
Oct 25, 2022