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University of Nebraska Medical Center

Category: Long COVID

A Reporter in Search of Long Covid’s Impact

(Bloomberg Prognosis/Jason Gale) While the evidence is still emerging, what’s clear already is that the social and economic impacts are profound. Harvard economist David Cutler puts the cost of long Covid at $3.7 trillion in the US alone. And the condition could impair more than 140 million people worldwide. 

Nov 3, 2022

U.S. government to test Pfizer’s Paxlovid for long COVID

(Reuters) The U.S. National Institutes of Health’s $1 billion RECOVER Initiative has picked Pfizer Inc’s (PFE.N) antiviral drug Paxlovid as the first treatment it will study in patients with long COVID, organizers of the study said on Thursday. The complex medical condition involves more than 200 symptoms ranging from exhaustion and cognitive impairment to pain, fever and […]

Oct 28, 2022

Long-COVID post-viral chronic fatigue and affective symptoms are associated with oxidative damage, lowered antioxidant defenses and inflammation: a proof of concept and mechanism study

(Nature) The immune-inflammatory response during the acute phase of COVID-19, as assessed using peak body temperature (PBT) and peripheral oxygen saturation (SpO2), predicts the severity of chronic fatigue, depression and anxiety symptoms 3–4 months later.

Oct 24, 2022

Dr Anthony Fauci: long Covid is an ‘insidious’ public health emergency

Guardian – Dr. Fauci urged US Congress to avoid complacency and resume funding to combat the virus as well as long Covid, a chronic and prolonged illness that continues to elude scientists and healthcare providers. “It’s a very insidious beneath-the-radar-screen public health emergency,” Fauci said via Zoom. “It isn’t that you have people who are […]

Oct 18, 2022

Outcomes among confirmed cases and a matched comparison group in the Long-COVID in Scotland study

Nature – With increasing numbers infected by SARS-CoV-2, understanding long-COVID is essential to inform health and social care support. A Scottish population cohort of 33,281 laboratory-confirmed SARS-CoV-2 infections and 62,957 never-infected individuals were followed-up via 6, 12 and 18-month questionnaires and linkage to hospitalization and death records. Of the 31,486 symptomatic infections,1,856 (6%) had not […]

Oct 13, 2022

Use of Cardiopulmonary Exercise Testing to Evaluate Long COVID-19 Symptoms in Adults

JAMA – In this systematic review and meta-analysis of 38 studies comprising 2160 participants, exercise capacity was reduced by 4.9 mL/kg/min among individuals with symptoms consistent with LC compared with individuals without symptoms more than 3 months after SARS-CoV-2 infection. Findings among individuals with exertional intolerance suggest that deconditioning, dysfunctional breathing, chronotropic incompetence, and abnormal […]

Oct 13, 2022

Studies suggest role for exercise testing in long COVID, impact of initial symptoms

CIDRAP – Two studies published today reveal new findings on long COVID, with one showing a possible role for cardiopulmonary exercise testing (CPET) for the evaluation of persistent symptoms, and the other finding a link between symptomatic infection and poor quality of life and reduced ability to complete daily activities. Continue reading

Oct 13, 2022

Long COVID Persists in People With Symptomatic SARS-CoV-2 Infection

MedPageToday – Long COVID — defined as one or more clusters of symptoms lasting 3 months or longer — occurred in about 6% of people with symptomatic SARS-CoV-2 infection, a modeling study based on 1.2 million global COVID patients showed. After adjusting for pre-COVID health status, an estimated 6.2% (95% uncertainty interval [UI] 2.4-13.3) of […]

Oct 11, 2022

Long COVID: Scientists find 20 blood protein ‘signatures’ that may point to risk

Med News Today – Researchers published their findings comparing blood samples from healthcare workers who had contracted SARS-CoV-2 and healthcare workers who had not. They found that blood protein levels within six weeks of contracting SARS-CoV-2 could predict long COVID incidence. “These changes in the blood that we observe shortly after infection indicate how the […]

Oct 4, 2022

Characteristics of long COVID among older adults: a cross-sectional study

International Journal of Infectious Diseases – 2333 individuals were evaluated at an average of 5 months [146 days (95% CI 142-150)] following COVID-19 onset. Mean age was 51 and 20.5% were>65 years. Older adults were more likely to be symptomatic, with most common symptoms being fatigue (38%) and dyspnea (30%). They were more likely to […]

Oct 4, 2022