Category: Avian Influenza Published Research
(Pathogens) Wild carnivore species infected with highly pathogenic avian influenza (HPAI) virus subtype H5N1 during the 2021–2022 outbreak in the Netherlands included red fox (Vulpes vulpes), polecat (Mustela putorius), otter (Lutra lutra), and badger (Meles meles). Most of the animals were submitted for testing because they showed neurological signs. In this study, the HPAI H5N1 […]
Feb 16, 2023
What Not to Ask Me About My Long COVID
(Atlantic) Before I got long COVID, I tuned out virtually all stories about it. They were tedious because I was tired of the pandemic, because we are all tired of the pandemic, because it is as familiar as rain and honestly just as dreary; I can hardly believe we once called the coronavirus novel. Today, I still tune […]
Feb 15, 2023
First Mass Mortality of Marine Mammals Caused by Highly Pathogenic Influenza Virus
PREPRINT Universidad Nacional del Comahue – San Carlos de Bariloche, Argentina. (Machine Translated) 1 First Mass Mortality of Marine Mammals Caused by Highly Pathogenic Influenza Virus2 (H5N1) in South AmericaVíctor Gamarra-Toledo1,2, Pablo I. Plaza1*, Giancarlo Inga3,4, Roberto Gutiérrez2,3 3 ,Oscar García-Tello3, Leonela Valdivia-Ramírez3, Deyvis Huamán-Mendoza3 4 , José C.Nieto-Navarrete3, Sandra Ventura3, Sergio A. Lambertucci1 567 […]
Feb 10, 2023
Highly pathogenic avian influenza A(H5N1) virus infection in farmed minks, Spain, October 2022
(Eurosurveillance) This report describes an outbreak of highly pathogenic avian influenza (HPAI) A(H5N1) detected in intensively farmed minks in Europe, which occurred in the Galicia region in northwest Spain in October 2022. We present an in-depth description of the epidemiological, clinical and genetic investigations of this outbreak affecting a single farm and discuss public health […]
Feb 8, 2023
Will mink-to-mink H5N1 flu on a farm in Spain spread ferret-to-ferret in a lab?
(ISDA) Last week, Aguero et al. reported in the journal Eurosurveillance that in October 2022, H5N1 avian influenza (clade 2.3.4.4b) caused mink-to-mink infections and some deaths (peak of 4.3%) on a farm with more than 51,000 mink in Galicia in northwest Spain. Although H5N1 “avian flu” has infected limited numbers of mammalian species, this is the first reported outbreak […]
Feb 8, 2023
(PLoS Pathogens) Global spread and regional endemicity of H5Nx Goose/Guangdong avian influenza viruses (AIV) pose a continuous threat for poultry production and zoonotic, potentially pre-pandemic, transmission to humans. Little is known about the role of mutations in the viral neuraminidase (NA) that accompanied bird-to-human transmission to support AIV infection of mammals. Here, after detailed analysis […]
Feb 8, 2023
H5N1 pathogenesis studies in mammalian models
(Virus Research) H5N1 influenza viruses are capable of causing severe disease and death in humans, and represent a potential pandemic subtype should they acquire a transmissible phenotype. Due to the expanding host and geographic range of this virus subtype, there is an urgent need to better understand the contribution of both virus and host responses […]
Dec 5, 2013
H5N1 Hybrid Viruses Bearing 2009/H1N1 Virus Genes Transmit in Guinea Pigs by Respiratory Droplet
(Science) Currently, there is anxiety that the avian H5N1 influenza virus will reassort with the highly transmissible and epidemic H1N1 subtype to trigger a virulent human pandemic. Y. Zhang et al. (p. 1459, published online 2 May) used reverse genetics to make all possible reassortants between a virulent bird H5N1 with genes from a human pandemic H1N1. Virulence was […]
May 2, 2013
Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets
(Science) Highly pathogenic avian influenza A/H5N1 virus can cause morbidity and mortality in humans but thus far has not acquired the ability to be transmitted by aerosol or respiratory droplet (“airborne transmission”) between humans. To address the concern that the virus could acquire this ability under natural conditions, we genetically modified A/H5N1 virus by site-directed […]
Jun 22, 2012
(Nature) An engineered influenza virus based on a haemagglutinin protein from H5N1 avian influenza, with just four mutations, can be transmitted between ferrets, emphasizing the potential for a human pandemic to emerge from birds. Influenza pandemics in humans arise from animal influenza viruses, yet the molecular changes required for an animal virus to be transmitted […]
May 2, 2012