Category: Clinical Considerations
Paxlovid Linked to Lower Risk of Long COVID
Contagion Live Treating COVID-19 with Paxlovid, a combination of nirmatrelvir with ritonavir, within 5 days of symptom onset was associated with lower risk for developing Post-COVID-19 Conditions (PCC), or Long COVID, in a large Veterans Affairs (VA) cohort study. In addition to reducing risk of mild to moderate infection becoming severe, and of severe symptoms requiring […]
Mar 28, 2023
Study finds co-infection with ‘superbug’ bacteria increases SARS-CoV-2 replication
Schulich School of Medicine and Dentistry Global data shows nearly 10 per cent of severe COVID-19 cases involve a secondary bacterial co-infection – with Staphylococcus aureus, also known as Staph A., being the most common organism responsible for co-existing infections with SARS-CoV-2. Researchers at Western have found if you add a ‘superbug’ – methicillin-resistant Staphylococcus […]
Mar 21, 2023
Nirmatrelvir-Ritonavir Effective Against Omicron BA.4, BA.5 SARS-CoV-2 Variant
Pulmonology Advisor Real-world evidence from the Omicron period of the COVID-19 pandemic shows the benefit of nirmatrelvir-ritonavir for vaccinated outpatients and those younger than 65 years of age with non-severe COVID-19 at high risk of hospitalization or death, according to study findings published in The Lancet Infectious Diseases. Investigators sought to examine the real-world effect of […]
Mar 21, 2023
SARS-CoV-2 infection weakens immune-cell response to vaccination
NIH NIH-funded study suggests need to boost CD8+ T cell response after infection. The magnitude and quality of a key immune cell’s response to vaccination with two doses of the Pfizer-BioNTech COVID-19 vaccine were considerably lower in people with prior SARS-CoV-2 infection compared to people without prior infection, a study has found. In addition, the […]
Mar 21, 2023
Persistent prosopagnosia following COVID-19
(Science Direct) Abstract COVID-19 can cause psychological problems including loss of smell and taste, long-lasting memory, speech, and language impairments, and psychosis. Here, we provide the first report of prosopagnosia following symptoms consistent with COVID-19. Annie is a 28-year-old woman who had normal face recognition prior to contracting COVID-19 in March 2020. Two months later, […]
Mar 14, 2023
SARS-CoV-2 is associated with changes in brain structure in UK Biobank
(Nature) There is strong evidence of brain-related abnormalities in COVID-191,2,3,4,5,6,7,8,9,10,11,12,13. However, it remains unknown whether the impact of SARS-CoV-2 infection can be detected in milder cases, and whether this can reveal possible mechanisms contributing to brain pathology. Here we investigated brain changes in 785 participants of UK Biobank (aged 51–81 years) who were imaged twice using […]
Mar 14, 2023
Bacterial co-infections cause twofold increase in mortality in COVID patients: study
Fierce Healthcare Though the COVID-19 pandemic appears to be ebbing significantly in the U.S., endemic COVID-19 still poses a challenge, experts say. Last Friday saw 31,443 new cases of COVID-19, while 344 people died from the disease, according to the Johns Hopkins Coronavirus Resource Center. Experts continue to measure the full effects of the pandemic. A study published last […]
Mar 7, 2023
What Scientists Know About Long COVID, 3 Years In
C-Net A puzzling disease left millions of patients trying to piece it together. Research is ongoing, but some causes and potential treatments are taking shape. For many people, what started out as a relatively mild case of COVID-19 persisted into a lingering condition that took weeks or months before their suffering subsided — some are […]
Mar 7, 2023
JAMA Question Do postacute sequelae of SARS-CoV-2 increase risks of 1-year adverse outcomes? Findings In this case-control study of 13 435 US adults with post–COVID-19 condition (PCC) and 26 870 matched adults without COVID-19, the adults with PCC experienced increased risks for a number of cardiovascular outcomes, such as ischemic stroke. During the 12-month follow-up period, 2.8% of the […]
Mar 7, 2023
Long Covid Patients More Likely to Have Gastrointestinal Problems, Study Finds
New York Times The study, which examined patients infected early in the pandemic, found they were significantly more likely than people who didn’t get Covid to experience lingering reflux, constipation and other issues. Stomach pain, constipation, diarrhea, vomiting, bloating — these are symptoms frequently reported by people with long Covid. Now, a large new study reports that […]
Mar 7, 2023