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University of Nebraska Medical Center

Could polio be poised for a comeback?

NPR The world is so close to wiping out polio. But in 2025, there are signs that the virus is not quite ready to go the way of smallpox — the only disease eradicated by humans.

Two countries are seeing an increase in cases caused by the wild polio virus, which can cause paralysis and even death, particularly in infants and young children.

And the cuts in USAID contracts that support polio vaccination raise concern that other countries will see a resurgence as well.

Even with in-country vaccination campaigns and global aid, Pakistan and Afghanistan have so far been unable to stop transmission of the disease. In 2024, Pakistan’s numbers spiked to 74 while Afghanistan saw 24 recorded polio cases. So far this year, Pakistan has reported 6 cases and Afghanistan has reported 1. These new cases are tied to disruptions in ongoing vaccine campaigns.

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