MedPageToday The modified vaccinia Ankara-Bavarian Nordic mpox vaccine (MVA-BN; Jynneos) generated robust immune responses in adolescents against mpox and was safe, according to an interim analysis of a phase II clinical trial.
Two doses of the vaccine generated geometric mean titers (GMT) in adolescents (470.3, 95% CI 422.3-523.8) that were higher than titers in adults (293.2, 95% CI 249.8-344.2), with a geometric mean titer ratio (GMTR) of 1.60 (95% CI 1.32-1.95), reported C. Mary Healy, MD of Baylor College of Medicine in Houston, during the IDWeek annual meeting in Los Angeles.