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University of Nebraska Medical Center

The Mosquito-Borne Disease ‘Triple E’ Is Spreading in the US as Temperatures Rise

Wired Eastern equine encephalitis, which has a high mortality rate, is becoming more common in North America as climate changes expands the habitats of insects. A 41-year-old man in New Hampshire died last week after contracting a rare mosquito-borne illness called eastern equine encephalitis virus, also known as EEE or “triple E.” It was New Hampshire’s first human case of the disease in a decade. Four other human EEE infections have been reported this year, in Wisconsin, New Jersey, Massachusetts, and Vermont. Though this outbreak is small, and triple E does not pose a risk to most people living in the United States, public health officials and researchers are concerned about the threat the deadly virus poses to the public, both this year and in future summers. There is no known cure for the disease, which can cause severe flu-like symptoms and seizures in humans four to 10 days after exposure and kills between 30 and 40 percent of the people it infects. Half of the people who survive a triple E infection are left with permanent neurological damage. Because of EEE’s high mortality rate, state officials have begun spraying insecticide in Massachusetts, where 10 communities have been designated “critical” or “high risk” for triple E. Towns in the state shuttered their parks from dusk to dawn and warned people to stay inside after 6 pm, when mosquitoes are most active.

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