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University of Nebraska Medical Center

Omicron, Now 2 Years Old, Is Not Done With Us Yet

New York Times

The dominant variant of the coronavirus has proved to be not only staggeringly infectious, but an evolutionary marvel.

By November 2021, nearly two years after the coronavirus emerged in Wuhan and spread across the world, the surprises seemed to be over. More than four billion people had been vaccinated against the virus, and five million had died. Two new variants, known as Alpha and Delta, had surged and then ebbed. As Thanksgiving approached, many Americans were planning to resume traveling for the holiday.

And then, the day after turkey, the pandemic delivered a big new surprise. Researchers in Botswana and South Africa alerted the world that a highly mutated version of the virus had emerged and was spreading fast. Omicron, as the World Health Organization called the variant, swiftly overtook other forms of the virus. It remains dominant now, on its second anniversary.

In the two years since its emergence, Omicron has proved to be not only staggeringly infectious, but an evolutionary marvel, challenging many assumptions virologists had before the pandemic. It has given rise to an impressive number of descendants, which have become far more adept at evading immunity and finding new victims.

“It was almost like there was another pandemic,” said Adam Lauring, a virologist at the University of Michigan.

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