Researchers uncovered an association between specific microRNAs and COVID-19 severity in a group of 259 unvaccinated patients. The team identified these microRNAs as crucial factors related to a weakened immune response and ICU admission.
This study provides the first genomic picture of blood microRNAs in COVID-19 patients from the Middle East, North Africa, and South Asia. The findings could pave the way for improved patient prognosis and treatment strategies, potentially benefitting approximately 30% of the global population.
Key Facts:
- Researchers created the first genomic blueprint of blood microRNAs in COVID-19 patients from MENA and South Asia.
- They found early infection changes in microRNAs, affecting blood traits and aiding virus proliferation.
- The study linked 97 miRNAs with eight blood phenotypes significantly tied to ICU admission.