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University of Nebraska Medical Center

A new COVID variant is on the rise. Here’s what to know about LP.8.1

The Conversation

More than five years since COVID was declared a pandemic, we’re still facing the regular emergence of new variants of the virus, SARS-CoV-2.

The latest variant on the rise is LP.8.1. It’s increasing in Australia, making up close to one in five COVID cases in New South Wales.

Elsewhere it’s become even more dominant, comprising at least three in five cases in the United Kingdom, for example.

So what is LP.8.1? And is it cause for concern? Let’s look at what we know so far.

An offshoot of Omicron

LP.8.1 was first detected in July 2024. It’s a descendant of Omicron, specifically of KP.1.1.3, which is descended from JN.1, a subvariant that caused large waves of COVID infections around the world in late 2023 and early 2024.

The World Health Organization (WHO) designated LP.8.1 as a variant under monitoring in January. This was in response to its significant growth globally, and reflects that it has genetic changes which may allow the virus to spread more easily and pose a greater risk to human health.

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