CDC Since January 1, 2024, the Democratic Republic of the Congo and several neighboring countries in Central and Eastern Africa have confirmed through laboratory testing more than 21,000 mpox cases and more than 65 deaths.
There have also been travel-associated cases in other parts of Africa, Europe, Asia, North America, and South America.
The risk of clade I mpox to the public in the U.S. remains low
- The first case of clade I mpox in the United States was detected in November 2024.
- The Georgia Department of Public Health reported the second case of clade I mpox in the U.S. in January 2025.
- The New Hampshire Department of Health and Human Services reported the third case of clade I mpox in February 2025.
- The New York State Department of Health reported the fourth case of clade I mpox in February 2025.