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University of Nebraska Medical Center

Why a teenager’s bird-flu infection is ringing alarm bells for scientists

Nature A strain of avian influenza is showing signs of adaptation to human hosts, but there is no evidence that it can transmit from person to person. In a children’s hospital in Vancouver, Canada, a teenager is in critical condition after being infected with an avian influenza virus that has researchers on high alert.

Viral genome sequences released last week suggest that the teenager is infected with an H5N1 avian influenza virus bearing mutations that might improve its ability to infect the human airway. If true, it could mean that the virus can rapidly evolve to make the jump from birds to humans.

It’s a worrying development but it doesn’t mean that a new pandemic is imminent, says immunologist Scott Hensley at the University of Pennsylvania in Philadelphia. At present, there is no sign that the virus — which is related but not identical to the H5N1 virus infecting US dairy cattle — has been transmitted from the sick adolescent to other people.

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