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University of Nebraska Medical Center

Could Avian Flu Cause Our Next Pandemic?

MedPageToday Colleagues, it’s time to wake up and smell the coffee. Or, for a true reality check, just scan the Department of Agriculture’s frequently-updated map and tablesopens in a new tab or window naming the many animals that have tested positive for highly pathogenic avian influenza (HPAI) in the U.S. since May 2022.

Finding influenza A/H5N1 in wild birds and waterfowl and poultry is nothing new, of course. During 2024, however, our country has seen its first-ever multi-state outbreak in dairy cows expressing milk heavily tainted with the virus, as well as illness, deaths, or detections in cats, goats, alpaca, skunks, and house mice, among others. The latest species found to harbor A/H5N1 was a backyard pig in Oregonopens in a new tab or window. Once euthanized, its tissues teeming with virus fueled further unease because pigs are classic mixing vessels in which human and avian flu viruses can recombine and form new, virulent strains.

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