MedPage Treatment with the antiviral remdesivir (Veklury) plus dexamethasone was linked to fewer deaths among patients hospitalized for COVID-19 compared with dexamethasone monotherapy, a retrospective study suggested.
Using propensity score matching, the drug duo was associated with an overall 26% reduction in mortality at 14 days (adjusted HR 0.74, 95% CI 0.69-0.78, P<0.0001) and an overall 24% reduction at 28 days (aHR 0.76, 95% CI 0.72-0.81, P<0.0001) when compared with dexamethasone alone, reported Andre Kalil, MD, MPH, of the University of Nebraska Medical Center in Omaha, and colleagues in Clinical Infectious Diseases