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University of Nebraska Medical Center

Scientists Show How Bird Flu Spreads Between Mammals — As H5N1 Pandemic Fears Grow

Forbes Scientists have proven how cows have spread H5N1 bird flu across the country and infected other cows, wild birds and even mammals like cats and raccoons, according to research published in Nature Wednesday, findings that suggest it may be capable of spreading effectively between people in the future as outbreaks on poultry and dairy farms spark concerns the virus could trigger a pandemic in humans. Using genomic data, computer modeling and data about the virus’ spread, researchers from Cornell University have shown how infected cows from Texas spread H5N1 avian influenza to a farm with healthy cows in Ohio, as well as to cats, a racoon and wild birds in the area.

It is one of the first times scientists have seen “evidence of efficient and sustained mammalian-to-mammalian transmission” of the H5N1 bird flu strain, said Diego Diel, an associate professor of virology at Cornell and one of the study’s authors.

While it primarily infects birds, the so-called highly pathogenic avian influenza strain is capable of infecting mammals—including humans—and Diel said repeated spillovers into mammals from birds or transmission between mammals raises the risk of the virus mutating in a way that “could lead adaptation to mammals, spillover into humans and potential efficient transmission in humans in the future.”

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