The recently updated COVID vaccines showed protection against serious virus-related outcomes in immunocompetent adults, data from the CDC’s IVY and VISION networks showed.
From September 2023 to January 2024, vaccine effectiveness (VE) against COVID-related emergency department or urgent care encounters landed at 47% (95% CI 44-50), while protection against hospitalizations associated with the coronavirus ranged from 43% (95% CI 27-56) to 52% (95% CI 47-57), reported Jennifer DeCuir, MD, PhD, of CDC’s National Center for Immunization and Respiratory Diseases, and colleagues. “The comparison group included both unvaccinated persons and persons who had received original monovalent or bivalent doses only,” the researchers wrote in the Morbidity and Mortality Weekly Report “Thus, these results support current CDC recommendations for updated COVID-19 vaccination, including among persons who have previously received original monovalent or bivalent COVID-19 vaccines and those who have never been vaccinated, irrespective of previous infection history.”