The U.S. Department of Agriculture’s (USDA) Animal and Plant Health Inspection Service (APHIS) released national research from its first year of studies and sampling of white-tailed deer (Odocoileus virginianus) for active infection of SARS-CoV-2, the virus that causes COVID-19. These studies show that SARS-CoV-2 is likely to have spread widely within the U.S. white-tailed deer population. Additionally, our research shows that SARS-CoV-2 was transmitted from humans to deer, mutated, and was potentially transmitted back to humans. This research is helping us understand if cervids, such as white-tailed deer, are acting as a host or “reservoir species,” meaning an animal host where the virus can survive and potentially change.
While experts are still learning about SARS-CoV-2 in animals, there is no evidence that animals play a significant role in spreading the virus to humans.
“APHIS’ work to answer critical animal and public health questions around SARS-CoV-2 is continued with this research,” said Dr. Mike Watson, APHIS’ acting Administrator. “However, additional research using a One Health approach is needed to understand what the risks are to wildlife conservation and public health with continued circulation of this disease in wildlife.”
APHIS is currently in Year 2 of this research and has expanded disease surveillance for SARS-CoV-2 to other members of the deer family and additional States, territories, and Tribes. During the first year of sampling, APHIS and partners sampled over 11,000 white-tailed deer for SARS-CoV-2. We detected the virus in 12.2% of white-tailed deer, and 31.6% had antibodies indicative of previous SARS-CoV-2 exposure. Year 1 surveillance data, questions and answers, and other information on the APHIS white-tailed deer surveillance program are available on the Agency website.
The collaboration between APHIS, state wildlife agencies, and others to conduct wildlife surveillance for SARS-CoV-2 is part of a more significant effort to strengthen our Nation’s ability to detect and respond to future emerging diseases in animals.
APHIS partnered with the University of Missouri and the Centers for Disease Control and Prevention (CDC) on a recently published study resulting from this surveillance, “Transmission of SARS-CoV-2 in free-ranging white-tailed deer in the United States.”
Between November 2021 and April 2022, APHIS, state and tribal wildlife agencies, the Ohio State University, and the University of Missouri conducted wildlife surveillance for SARS-CoV-2 in free-ranging white-tailed deer, collecting more than 9,000 respiratory samples in 27 states. We found that SARS-CoV-2 was transmitted from humans to white-tailed deer at least 106 times in the United States, mutated, and then in three instances may have been transmitted back to humans. This study is available online at: https://www.nature.com/articles/s41467-023-39782-x.