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HPAI H5N1 (Avian Influenza)

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Discover comprehensive information and resources on HPAI H5N1 (Avian Influenza), including updates, situational reports, news, and published research. Explore this page to stay informed about the latest developments and insights HPAI H5N1. 

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About HPAI H5N1 

According to the Centers for Disease Control and Prevention (CDC), "Avian influenza or bird flu refers to the disease caused by infection with avian (bird) influenza (flu) Type A viruses. These viruses naturally spread among wild aquatic birds worldwide and can infect domestic poultry and other bird and animal species. Bird flu viruses do not normally infect humans. However, sporadic human infections with bird flu viruses have occurred."

The Highly Pathogenic Avian Influenza (HPAI) H5N1 strain is currently spreading globally, impacting both wild birds and domestic poultry. The virus has also been detected in wild mammals, including cows, foxes, mink, skunks, bears, sea lions, and otters, as well as in domestic cats and dogs. As of January 8, 2025, the United States has reported 66 confirmed human cases, including one fatality linked to the virus.

The CDC further explains "the wide geographic spread of A(H5N1) bird flu viruses in wild birds, poultry, and some other mammals, including in cows, is creating additional opportunities for people to be exposed to these viruses. Therefore, there could be an increase in sporadic human infections resulting from bird, cattle, and other animal exposures, even if the risk of these viruses spreading to people has not increased. Sporadic human infections in the current context would not significantly change CDC’s risk assessment." 

 

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Unofficial HPAI H5N1 Map
 
Unofficial HPAI H5N1 Map
Data was sourced and imported from FAO EMPRES, USDA APHIS, WAHIS, and open source news reports beginning in late 2022 to current.

 

 
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Published Papers

 

Prosser, D.J., Teitelbaum, C.S., Yin, S. et al. Climate change impacts on bird migration and highly pathogenic avian influenza. Nat Microbiol 8, 2223–2225 (2023). https://doi.org/10.1038/s41564-023-01538-0
Vreman, S.; Kik, M.; Germeraad, E.; Heutink, R.; Harders, F.; Spierenburg, M.; Engelsma, M.; Rijks, J.; van den Brand, J.; Beerens, N. Zoonotic Mutation of Highly Pathogenic Avian Influenza H5N1 Virus Identified in the Brain of Multiple Wild Carnivore Species. Pathogens 202312, 168. https://doi.org/10.3390/pathogens12020168
Agüero MontserratMonne IsabellaSánchez AzucenaZecchin BiancaFusaro AliceRuano María Josédel Valle Arrojo ManuelFernández-Antonio RicardoSouto Antonio ManuelTordable PedroCañás JulioBonfante FrancescoGiussani EdoardoTerregino CalogeroOrejas Jesús Javier. Highly pathogenic avian influenza A(H5N1) virus infection in farmed minks, Spain, October 2022. Euro Surveill. 2023;28(3):pii=2300001. https://doi.org/10.2807/1560-7917.ES.2023.28.3.2300001