Integrative Physiology and Molecular Medicine Faculty
Faculty Departments
- Biochemistry and Molecular Biology
- Cellular and Integrative Physiology
- College of Dentistry
- College of Nursing
- College of Pharmacy
- College of Public Health
- Emergency Medicine
- Eppley Institute
- Genetics Cell Biology and Anatomy
- Internal Medicine
- Munroe-Meyer Institute
- Obstetrics and Gynecology
- Ophthalmology and Visual Sciences
- Pathology, Microbiology, and Immunology
- Pediatrics
- Pharmacology and Experimental Neuroscience
- Radiology
- Surgery
Faculty
Windy Alonso, PhD, RN Research focus: Understanding heart failure with preserved ejection fraction; developing interventions to promote exerciese in adults with heart failure that can be applied in diverse and underserved settings. |
|
Daniel R. Anderson, MD, PhD Research focus: Molecular and cellular immunology; innate immunity (preexisting immunity) and how such immune responses contribute to the mechanisms of cardiovascular disease processes, specifically focused on underlying mechanisms of viral myocarditis, atherosclerotic disease and the impact inflammation has on cardiac rhythm abnormalities. |
|
Ann Anderson Berry, MD, PhD Research focus: Nutrition of the ELBW infant, preterm infant protein requirements, human milk fortification, Vitamin D metabolism in the mother infant dyad, Vitamin A deficiency, Vitamin E metabolism. |
|
Pooneh Bagher, PhD Research focus: Vascular function; calcium imaging; extreme physiology. |
|
Christopher Barrett, MD Research focus: Interface of coagulation, fibrinolysis and inflammatory perturbations after traumatic injury and major surgery at the molecular and cellular level. |
|
Robert Bennett, PhD Research focus: Antifibrotic effects of the hormone relaxin and related peptides; expression and signaling of relaxin receptors; internalization and degradation of relaxin, insulin and related hormones; the role of relaxin in adipose function. |
|
Keshore Bidasee, PhD Research focus: Delineating the pathogenic trajectories that contribute to vascular diseases in organs including the brain, heart, kidney, and lung during HIV-1 infection and diabetes mellitus. |
|
Erika I. Boesen, PhD Research focus: Iron-medicated kidney damage in lupus nephritis; renal control of salt and water homeostasis. |
|
Keely Buesing, MD, FACS Research focus: Large animal and pulmonary cellular investigation of novel therapeutics targeting Acute Respiratory Distress Syndrome (ARDS). |
|
John S. Davis, PhD Research focus: Women's health; Reproductive endocrinology and cancer; Mechanisms of hormone action. |
|
Paul Denton, PhD Research focus: Improving immunotherapies to treat malignancies. |
|
Cyrus Desouza, MBBS Research focus: Improving outcomes in diabetes and obesity patients using treatment algorithms; mechanisms of diabetes and metabolic syndrome on vascular and brain function. |
|
Andrew Dudley, PhD Research focus: Mechanisms that regulate the development and homeostasis of musculoskeletal tissue using methods from embryology, molecular biology, cell biology, genetics and tissue engineering, with the goal of generating novel therapies for regenerative medicine. |
|
Lie Gao, MD, PhD Research focus: Role of skeletal muscle Nrf2 in exercise-induced cardioprotection, with a focus of extracellular vesicle-mediated cell-to-cell antioxidant communication, by employing skeletal muscle-specific transgenic mouse lines. |
|
Howard E. Gendelman, MD Research focus: Development and testing of HIV-1 cure strategies; Basic and clinical studies on novel medicines to treat Parkinson's disease. |
|
Karen Gould, PhD Research focus: Estrogen receptor alpha regulation of B cell receptor signaling, B cell fate, and lupus pathogenesis. B cell transcriptomics and genomics. |
|
Rebekah Gundry, PhD Research focus: Development and application innovative mass spectrometry (MS) technologies, bioinformatics tools, and methodologies to transform our understanding of cell surface proteins and glycans, and answer outstanding questions in stem cell biology and cardiac pathology. |
|
Lynda Harris, PhD Research focus: Studying placental function in animals and humans; developing obstetric nanomedicines, placental-specific drug delivery systems and other treatments for placental dysfunction.. |
|
Curtis Hartman, MD Research focus: Management of infected hip and knee replacements. |
|
Peter Kador, PhD Research focus: Design and synthesis of multifunctional antioxidants and enzyme inhibitors; the mechanism of action drugs and development of agents as they relate to the inhibition of diabetic complications; age related macular degeneration, cataract development and neurodegeneration, including Alzheimer’s disease; basic cellular mechanisms that lead to the initiation of diabetic complications and the development of disease-associated animal models. |
|
Kusum Kharbanda, PhD Research focus: Alcohol liver injury with emphasis on alcohol's deleterious effect in altering the methionine metabolic pathway and lowering the ratio of the methyl donor, SAM, to its product, SAH. |
|
Tammy L. Kielian, PhD Research focus: Host-pathogen interactions, immunology, neuroimmunology, translational therapeutics. |
|
Robert Lewis, PhD Research focus: Defining intracellular mechanisms required for the epithelia-mesenchymal transition (EMT) and the formation and maintenance of cancer stem cells. |
|
Yulong Li, MD Research focus: Regulatory role of the peripheral nervous system in peripheral tissues (such as myocardium and skeletal muscle) in pathophysiological conditions, including heart failure, diabetes, ischemia-reperfusion injury, and peripheral artery disease. |
|
Steven Lisco, MD Research focus: Critical Care Management, thoracic and vascular anesthesiology, management of complex airways, blood management. |
|
Brian Lowes, MD, PhD Research focus: Novel education clinical trainees and education program with a goal to develop clinicians and scientists in sub-Saharan Africa. |
|
Sidharth Mahapara, MD, PhD Research focus: Elucidating pathophysiologic mechanisms triggering aggressive pediatric brain tumors using transcriptomic analyses to hone in on essential signaling pathways and to test synthetic inhibitors of these pathways; Repurposing FDS-approved drugs for treatment of aggressive pediatric brain tumors. |
|
Ram Mahato, PhD Research focus: Micelle and nanoparticle drug delivery; Oligonucleotides, siRNA, miRNA, and gene delivery; Synthesis of novel polymers, lipopeptides, lipopolymers and cationic lipids; Construction of gene and shRNA expression systems; Design and synthesis new compounds to overcome chemoresistance and inhibit hedgehog signaling pathway. |
|
Roslyn Mannon, MD Research focus: Mechanisms of long term kidney allograft injury both immunological and nonimmunological using in vitro studies. |
|
David McMillan, PhD Research focus: Mechanisms of toxicity of drugs and environmental chemicals; mechanism underlying pro-oxidant drug-induced hemolytic anemia , and in the metabolism and toxicity of the environmental contaminant, trichloroethylene. |
|
Paras Kumar Mishra, PhD Research focus: MicroRNomics of cardiovascular diseases and diabetic cardiomyopathy. |
|
Daniel T. Monaghan, PhD Research focus: Development of drugs for modulating NMDA receptor activity for treating schizophrenia and autism. |
|
R. Lee Mosley, PhD Research focus: Regulation of T Lymphocyte function; T cell-mediated immunity in neurodegenerative disorders. |
|
Robert B. Norgren, PhD Research focus: Use of nonhuman primate genomics to better understand human genetic disease. |
|
Song-Young Park, PhD Research focus: Endothelial mitochondrial function; reactive oxygen species; aging; peripheral artery disease; spinal cord. |
|
Kaushik P. Patel, PhD Research focus: Neural control of circulation; neural regulation of cardiovascular and renal function in health and disease states. |
|
Gurudutt N. Pendyala, PhD Research focus: Animal models of addiction, sex differences in drug abuse; Synaptic biology; Epigenetic regulation, role of microRNAs at the synapse in drug addiction, mechanisms and role in gene regulation; Prenatal drug exposure and synaptic development; Integrative Systems Biology approach to understand synaptic aberrations in chronic drug abuse; High input technologies-genomics, mass spectrometry-based proteomics and metabolomics. |
|
Armen Petrosyan, MD, PhD Research focus: Mechanism of Golgi alteration in advanced prostate cancer: focus on aberrant glycosylation; role for non-muscle Myosin IIA in alcohol-induced Golgi fragmentation. |
|
Iraklis Pipinos, MD, PhD Research focus: Development of regenerative medicine strategies for skeletal muscle tissues in the legs of patients suffering from peripheral arterial disease (PAD). |
|
Thomas Porter, MD Research focus: Targeted blood brain barrier permeability changes with ultrasound and microbubbles. |
|
Bunny Pozehl, PhD, RN, APRN-NP, FAHA, FAAN Research focus: Exercise training interventions and promoting adherence to exercise in hear t failure. |
|
Subu Ramanathan, PhD Research focus: Principles that underpin how cells with divergent sizes pack into epithelial tissue and how alterations in cellular packing influence tissue homeostasis. |
|
Stephen I. Rennard, MD Research focus: Cellular mechanisms that underlie altered tissue structure in lung disease, particularly with regard to chronic obstructive pulmonary disease (COPD). |
|
William Rizzo, MD Research focus: Sjogren-Larsson Syndrome and other inherited metabolic diseases. |
|
Debra Romberger, MD Research focus: Agricultural/occupation/environmental lung disease; airway epithelial repair and injury mechanisms; clinical problems associated with COPD. |
|
Shyamal K. Roy, PhD Research focus: Endocrine regulation of follicular development, growth factors, signal transduction in ovarian cells and biochemistry of granulosa cells. |
|
Ruxana Sadikot, MD Research focus: Defining the lung immune response; Mechanism of lung injury. |
|
Jeffrey Salomon, MD Research focus: Map the microbiome in patients with congenital heart disease; Link dysbiosis and inflammatory metabolites in intestinal barrier dysfunction and subsequent increased systemic inflammation; Identify targets in the intestinal milieu aimed at recuding the inflammatory cascade in patients with congenital heart disease. |
|
Steven C. Sansom, PhD Research focus: Physiological mechanisms of ion transport in the kidney. |
|
Alicia Schiller, PhD Research focus: Quantification of sympathetic nervous system output and vascular control for clinically relevant applications, including intraprocedural feedback for renal denervation, hemorrhage, and as a screening tool for the presence of dysautonomia. |
|
Micah Schott, PhD Research focus: Cell biology of lipids in metabolic disease. |
|
Harold D. Schultz, PhD Research focus: Sensory and motor functions of the autonomic nervous system. |
|
Aleem Siddique, MBBS Research focus: Lung transplant outcomes; Short and long term mechanical support outcomes; Graft patency and coronary bypass surgery (CABG) outcomes. |
|
Kelly Stauch, PhD Research focus: Role of mitochondrial dysfunction and altered energy metabolism in the context of neurodegenerative diseases adn aging. |
|
Geoffrey M. Thiele, PhD Research focus: Autoimmunity, immune system disorders, immunopathology; infectious diseases/agents; Rheumatoid arthritis, atherosclerosis, breast cancer and the immune system, bone loss and erosion, alcoholic liver disease. |
|
Wallace B. Thoreson, PhD Research focus: Visual information processing by the retina; electrophysiology and optical imaging techniques to study transmission at ribbon synapses of rod and cone photoreceptors. |
|
Matthew Van Hook, PhD Research focus: Influence of neurodegenerative disease of the visual system (i.e. glaucoma) on the function of neurons and synapses i the brain and retina. |
|
Joseph Vetro, PhD Research focus: Developing novel synthetic targeted drug and gene delivery nanocarriers for the anti-angiogenesis treatment of cancer; improving development paradigms for targeted bioimaging and drug delivery nanocarriers; developing subunit vaccines based on the novel adjuvant, EP67. |
|
Saraswathi Viswanathan, PhD Research focus: Determine the role of obesity in modulating the pathogenesis of insulin resistance, alcohol-associated liver injury, and pancreatic cancer. |
|
Hanjun Wang, PhD Research focus: Exercise physiology; cardiovascular research; respiratory research; neuroal science. |
|
Ying Yan, PhD Research focus: Tumorigenesis, cancer progression and metastasis, and development of new anticancer agents. |
|
Sowmya Yelamanchili, PhD Research focus: MicroRNAs in neurodegenerative disease, HIV, Parkinson's Disease. |
|
Chi (Kevin) Zhang, MD, PhD Research focus: Development of novel strategies for delivery of therapies to brain tumors. |
|
Siwei Zhao, PhD Research focus: Developing novel electrical engineering technologies to facilitate localized drug delivery, chronic wound healing and neural/muscular rehabilitation after peripheral nerve injury. |
|
Matthew C. Zimmerman, PhD Research focus: Role of reactive oxygen species and redox signaling in the brain in the pathogenesis of cardiovascular disease; utilization of nanoformulated antioxidants for the improved treatment of cardiovascular disease. |
|
Irving H. Zucker, PhD Research focus: Neural control of cardiovascular function; heart failure; hypertension; sympathetic function. |
|