Vimla Band, PhD
Ardith and Anna Von Housen Professor and Chairwoman
Chair, Department of Genetics, Cell Biology, and Anatomy
Professor, Department of Genetics, Cell Biology, and Anatomy
Dr. Vimla Band received her PhD in Pharmacology from All-India Institute of Medical Sciences, New Delhi India, followed by receiving her postdoctoral training in Cancer Genetics from Harvard Medical School. She joined as Assistant Professor at the New England Medical Center, Tufts University School of Medicine in 1991. In 2003, she joined as a Professor at Feinberg School of Medicine and Evanston Northwestern Healthcare, Northwestern University. In 2007, she joined as Professor and Vice Chair of Research in the Department of Genetics, Cell Biology, and Anatomy (GCBA), UNMC. She became Professor and Chairwoman in year 2010. She is an author of over 180 publications, serves/served on numerous National Institute of Health and Department of Defense Breast Cancer program review panels. She is an editorial board member of four journals. She is continuously funded by NIH/DOD since 1991. Dr. Band’s research is focused on molecular mechanisms of breast cancer progression.
- Post-doc, Cancer Genetics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
- PhD, Pharmacology, All India Institute of Medical Sciences, India
- MSc, Pharmacology, All India Institute of Medical Sciences, India
- BS, Medical Technology, All India Institute of Medical Sciences, India
The major focus of Dr. Band's laboratory is to delineate the molecular basis of normal epithelial cell transformation to malignant cell.
In recent years laboratory's focus is to dissect molecular mechanism of the role of mammalian Ecdysoneless (ECD) in mRNA biogenesis to facilitate cell cycle progression and cell survival of cancer cells.
- Mohapatra BC, Mirza, Bele A, Gurumurthy CB, Raza M, Saleem I, Storck MD, Sarkar A, Kolala SS, Shukla SK, Southekal S, Wagner KU, Qiu F, Lele SM, Alsaleem MA, Rakha EA, Guda C, Singh PK, Cardiff RD, Band H and Band V. ECD overexpression drives mammary tumorigenesis through upregulation of c-MYC and glucose metabolism. Mol Cancer Res. 2022. Sep 2;20(9):1391-1404.
- Mirza S, Kalluchi A, Raza M, Saleem I, Pal D, Mohapatra B, Sarkar A, Lele S, Quellette M, Qiu F, Yu L, Lobanov A, Zheng Z-M, Zhang Y, Alsaleem MA, Rakha EA, Band H, Rowley MJ and Band V. Ecdysoneless protein regulates viral and cellular mRNA splicing to promote cervical oncogenesis. Mol Cancer Res. 2022 Feb;20(2):305-318.
- Saleem I, Mirza S, Sarkar A, Raza M, Mohapatra B, Mushtaq I, Kim JH, Mishra NK, Alsaleem MA, Rakha EA, Qiu F, Guda C, Band H and Band V. The mammalian ecdysoneless protein interacts with RNA helicase DDX39A to regulate nuclear mRNA export. Mol. Cell. Biol. 2021 Jun 23;41(7):e0010321.
- Outstanding Woman Scientist in Cancer Research, American Association of Indian Scientists in Cancer Research (AAISCR), 2014
- Certification in “Executive Leadership in Academic Medicine”, 2014