— Eppley Institute for Research in Cancer and Allied Diseases — About Us — Faculty — Xu Luo, PhD

Xu Luo, PhD

Professor, UNMC Eppley Institute for Research in Cancer and Allied Diseases
Research focus: Molecular mechanisms and signaling pathways in cell death and survival in cancer cells

Send Email

Phone: 402-559-4643

Xu Luo, PhD, is a professor in the UNMC Eppley Institute for Research in Cancer and Allied Diseases, and holds courtesy appointments in the UNMC departments of Genetics, Cell Biology and Anatomy, and Pathology and Microbiology.

Education

PhD, University of Texas, MD Anderson Cancer Center and Health Science Center at Houston

Research Interests

Our laboratory uses biochemical, genetic, and cell biology approaches to investigate the molecular mechanisms of cell death and survival in cancer cells. The Bcl-2 family proteins, which are classified into BH3-only, effectors Bax/Bak, and anti-apoptotic Bcl-2 proteins, are of particular interest to us. We aim to understand how these proteins function as major regulators of cell death and survival, and hope to contribute to the design of more powerful and selective cancer therapeutic drugs.